Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 8/20 | 0.63 |
| ▸ | HTR7 | P34969 | 3/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434855 | 0.82 | SLC40A1 (0.62) | SLC40A1 | |
| SCHEMBL18434500 | 0.81 | SLC40A1 (0.63) | SLC40A1KDM4EALDH1A1 | |
| SCHEMBL18434469 | 0.79 | SLC40A1 (0.64) | SLC40A1 | |
| SCHEMBL11973453 | 0.77 | SLC40A1 (1.00) | SLC40A1 | |
| SCHEMBL18434697 | 0.76 | SLC40A1 (0.67) | SLC40A1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL18434485 | 0.75 | SLC40A1 (0.67) | SLC40A1DRD2 | |
| SCHEMBL18434826 | 0.74 | SLC40A1 (0.63) | SLC40A1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12475058 | 0.74 | SLC40A1 (0.55) | SLC40A1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL18434472 | 0.74 | KDM4E (0.39) | SLC40A1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL18434664 | 0.74 | SLC40A1 (0.55) | SLC40A1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |