Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 7/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434621 | 0.88 | SLC40A1 (0.65) | SLC40A1HTR1ADRD2DRD3SLC6A4 | |
| SCHEMBL18434854 | 0.83 | SLC40A1 (0.59) | SLC40A1MEN1CASP1KMT2ASMN1; SMN2 | |
| SCHEMBL18434505 | 0.81 | SLC40A1 (0.60) | SLC40A1 | |
| SCHEMBL18434712 | 0.78 | SLC40A1 (0.64) | SLC40A1MEN1USP2LMNACASP7 | |
| SCHEMBL18434692 | 0.75 | SLC40A1 (0.67) | SLC40A1APP | |
| SCHEMBL18434660 | 0.71 | SLC40A1 (0.53) | SLC40A1MEN1LMNAKMT2A | |
| SCHEMBL18434688 | 0.71 | SLC40A1 (0.53) | SLC40A1MEN1USP2LMNAKMT2A | |
| SCHEMBL18434485 | 0.67 | SLC40A1 (0.67) | SLC40A1HTR1ADRD2DRD3SLC6A4 | |
| SCHEMBL18434701 | 0.67 | SLC40A1 (0.67) | SLC40A1USP2CASP7SMN1; SMN2 | |
| SCHEMBL11973086 | 0.66 | SLC40A1 (1.00) | SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |