Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.67 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMYD2 | Q9NRG4 | 4/20 | 0.41 |
| ▸ | WNT1 | P04628 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | POLR1A | O95602 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434693 | 0.81 | SLC40A1 (0.69) | SLC40A1PARP1NPSR1SMYD2WNT1 | |
| SCHEMBL11997105 | 0.80 | SLC40A1 (1.00) | SLC40A1PARP1 | |
| SCHEMBL18434712 | 0.76 | SLC40A1 (0.64) | SLC40A1PARP1KDM4EHSD17B10 | |
| SCHEMBL18434854 | 0.75 | SLC40A1 (0.59) | SLC40A1KDM4E | |
| SCHEMBL18434820 | 0.75 | SLC40A1 (0.49) | SLC40A1APP | |
| SCHEMBL18434470 | 0.71 | SLC40A1 (0.72) | SLC40A1PARP1NPSR1WNT1DYRK1A | |
| SCHEMBL18434468 | 0.70 | SLC40A1 (0.70) | SLC40A1PARP1NPSR1WNT1DYRK1A | |
| SCHEMBL18434621 | 0.70 | SLC40A1 (0.65) | SLC40A1 | |
| SCHEMBL11995698 | 0.69 | SLC40A1 (1.00) | SLC40A1 | |
| SCHEMBL18434688 | 0.69 | SLC40A1 (0.53) | SLC40A1PARP1NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |