Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 7/20 | 0.67 |
| ▸ | RAD52 | P43351 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | WNT1 | P04628 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CCNK | O75909 | 1/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434500 | 0.82 | SLC40A1 (0.63) | SLC40A1RAD52ALDH1A1KDM4E | |
| SCHEMBL18434693 | 0.82 | SLC40A1 (0.69) | SLC40A1KDM4EWNT1DYRK1A | |
| SCHEMBL11997104 | 0.80 | SLC40A1 (1.00) | SLC40A1 | |
| SCHEMBL11973826 | 0.79 | KDM4E (0.46) | SLC40A1KDM4E | |
| SCHEMBL18434855 | 0.77 | SLC40A1 (0.62) | SLC40A1 | |
| SCHEMBL18434824 | 0.76 | SLC40A1 (0.63) | SLC40A1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL18434844 | 0.74 | SLC40A1 (0.63) | SLC40A1RAD52ALDH1A1KDM4E | |
| SCHEMBL18434469 | 0.73 | SLC40A1 (0.64) | SLC40A1 | |
| SCHEMBL18434472 | 0.72 | KDM4E (0.39) | SLC40A1HTTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL18434826 | 0.72 | SLC40A1 (0.63) | SLC40A1HTTALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |