Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | ACP1 | P24666 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434703 | 0.81 | SLC40A1 (0.69) | SLC40A1KDM4EL3MBTL1MITFPOLB | |
| SCHEMBL11973775 | 0.80 | SLC40A1 (1.00) | SLC40A1 | |
| SCHEMBL18434712 | 0.80 | SLC40A1 (0.64) | SLC40A1KMT2ALMNASMARCA2KDM4E | |
| SCHEMBL18434504 | 0.79 | SLC40A1 (0.62) | SLC40A1MAPTTSHRMAPK1 | |
| SCHEMBL18434857 | 0.79 | SLC40A1 (0.49) | SLC40A1LMNAKDM4EL3MBTL1POLB | |
| SCHEMBL18434826 | 0.78 | SLC40A1 (0.63) | SLC40A1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL18434500 | 0.78 | SLC40A1 (0.63) | SLC40A1KDM4EACP1POLBTOP2A | |
| SCHEMBL18434803 | 0.75 | SLC40A1 (0.66) | SLC40A1LMNAKDM4EALDH1A1TSHR | |
| SCHEMBL18434693 | 0.75 | SLC40A1 (0.69) | SLC40A1KMT2AKDM4EMEN1PARP1 | |
| SCHEMBL18434849 | 0.71 | SLC40A1 (0.60) | SLC40A1KMT2AKDM4EL3MBTL1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |