Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.66 |
| ▸ | PLAUR | Q03405 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434857 | 0.86 | SLC40A1 (0.49) | SLC40A1ALDH1A1LMNATSHRKDM4E | |
| SCHEMBL11973826 | 0.81 | KDM4E (0.46) | SLC40A1KDM4E | |
| SCHEMBL18434504 | 0.81 | SLC40A1 (0.62) | SLC40A1TSHR | |
| SCHEMBL11973290 | 0.80 | SLC40A1 (1.00) | SLC40A1 | |
| SCHEMBL18434473 | 0.79 | SLC40A1 (0.68) | SLC40A1ALDH1A1LMNATSHRKDM4E | |
| SCHEMBL18434483 | 0.75 | SLC40A1 (0.50) | SLC40A1SMN1; SMN2 | |
| SCHEMBL18434714 | 0.75 | SLC40A1 (0.66) | SLC40A1ALDH1A1LMNATSHRKDM4E | |
| SCHEMBL18434693 | 0.74 | SLC40A1 (0.69) | SLC40A1KDM4E | |
| SCHEMBL18434472 | 0.74 | KDM4E (0.39) | SLC40A1ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL18434849 | 0.73 | SLC40A1 (0.60) | SLC40A1ALDH1A1TSHRKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |