Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434803 | 0.86 | SLC40A1 (0.66) | SLC40A1SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL11973554 | 0.81 | SLC40A1 (0.75) | SLC40A1 | |
| SCHEMBL11973826 | 0.79 | KDM4E (0.46) | SLC40A1KDM4EL3MBTL1RAB9A | |
| SCHEMBL18434714 | 0.79 | SLC40A1 (0.66) | SLC40A1MAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL18434504 | 0.78 | SLC40A1 (0.62) | SLC40A1MAPTTSHR | |
| SCHEMBL18434693 | 0.76 | SLC40A1 (0.69) | SLC40A1KDM4ENPSR1APP | |
| SCHEMBL18434472 | 0.72 | KDM4E (0.39) | SLC40A1MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL18434697 | 0.71 | SLC40A1 (0.67) | SLC40A1SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL18434849 | 0.71 | SLC40A1 (0.60) | SLC40A1MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL18434448 | 0.70 | SLC40A1 (0.61) | SLC40A1MAPTSMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |