Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 13/20 | 0.51 |
| ▸ | PPARG | P37231 | 5/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL184592 | 0.90 | GCK (0.51) | GCKPPARGPPARA | |
| SCHEMBL185010 | 0.90 | GCK (0.48) | GCKPPARGPPARASOS1 | |
| SCHEMBL184498 | 0.87 | GCK (0.63) | GCKPPARGPPARA | |
| SCHEMBL197390 | 0.84 | GCK (0.50) | GCK | |
| SCHEMBL184337 | 0.81 | GCK (0.49) | GCKPPARGPPARA | |
| SCHEMBL184640 | 0.80 | GCK (0.50) | GCKPPARG | |
| SCHEMBL2657739 | 0.80 | GCK (0.58) | GCK | |
| SCHEMBL2656066 | 0.80 | GCK (0.61) | GCK | |
| SCHEMBL2657532 | 0.80 | GCK (0.52) | GCK | |
| SCHEMBL184731 | 0.80 | GCK (0.50) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402327-B1 | Acetamide compounds as glucokinase activators, their process and medicinal applications | IMPETIS BIOSCIENCES LTD (IN) | 2018-03-07 | — | — | EP | disclosed |
| EP-2402327-A1 | Acetamide compounds as glucokinase activators, their process and medicinal applications | Advinus Therapeutics Private Limited (IN) | 2012-01-04 | — | — | EP | disclosed |