Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 9/20 | 0.63 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL184640 | 0.88 | GCK (0.50) | GCKPPARGELOVL6 | |
| SCHEMBL184592 | 0.88 | GCK (0.51) | GCKPPARGPPARA | |
| SCHEMBL184731 | 0.87 | GCK (0.50) | GCKKMT2AKEAP1NFE2L2ELOVL6 | |
| SCHEMBL184906 | 0.87 | MMP13 (0.51) | GCKKEAP1NFE2L2ELOVL6 | |
| SCHEMBL197390 | 0.87 | GCK (0.50) | GCKKEAP1NFE2L2 | |
| SCHEMBL184497 | 0.87 | GCK (0.51) | GCKPPARGPPARA | |
| SCHEMBL185010 | 0.85 | GCK (0.48) | GCKPPARGPPARA | |
| SCHEMBL185529 | 0.84 | GCK (0.48) | GCKPPARGPPARAKEAP1NFE2L2 | |
| SCHEMBL184976 | 0.84 | GCK (0.48) | GCKPPARGMEN1KMT2AKEAP1 | |
| SCHEMBL11748683 | 0.82 | PPARG (0.51) | GCKPPARGPPARAMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402327-B1 | Acetamide compounds as glucokinase activators, their process and medicinal applications | IMPETIS BIOSCIENCES LTD (IN) | 2018-03-07 | — | — | EP | disclosed |
| EP-2402327-A1 | Acetamide compounds as glucokinase activators, their process and medicinal applications | Advinus Therapeutics Private Limited (IN) | 2012-01-04 | — | — | EP | disclosed |