Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5550993 | 0.95 | MAPT (0.38) | MAPTKMT2AALDH1A1NR4A1RAB9A | |
| SCHEMBL1845404 | 0.93 | KMT2A (0.43) | MAPTKMT2AALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL7936515 | 0.92 | KEAP1 (0.42) | KEAP1NFE2L2MAPTKMT2AALDH1A1 | |
| SCHEMBL5549293 | 0.91 | MAPT (0.39) | KEAP1NFE2L2MAPTKMT2AALDH1A1 | |
| SCHEMBL5645606 | 0.90 | MAPT (0.35) | KEAP1NFE2L2MAPTKMT2AALDH1A1 | |
| SCHEMBL7971698 | 0.90 | MAPT (0.38) | KEAP1NFE2L2MAPTKMT2AALDH1A1 | |
| SCHEMBL7970242 | 0.89 | L3MBTL1 (0.37) | KEAP1NFE2L2MAPTKMT2AALDH1A1 | |
| SCHEMBL7479868 | 0.88 | MEN1 (0.40) | MAPTKMT2AALDH1A1RAB9AMEN1 | |
| SCHEMBL1848196 | 0.87 | PLA2G2A (0.41) | MAPTKMT2AALDH1A1L3MBTL1MEN1 | |
| SCHEMBL5551024 | 0.85 | KMT2A (0.42) | MAPTKMT2AALDH1A1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971914-B1 | NEUTRAL COLOURING PHOTOCHROMIC 2H-NAPHTHO 1,2-b PYRANS AND HETEROCYCLIC PYRANS | VIVIMED LABS EUROP LTD (GB) | 2011-05-18 | — | — | EP | disclosed |