Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7936515 | 0.93 | KEAP1 (0.42) | SLC16A3MAPTKDM4EALDH1A1AKR1C3 | |
| SCHEMBL1845404 | 0.92 | KMT2A (0.43) | MAPTKDM4EALDH1A1AKR1C3HTT | |
| SCHEMBL7479868 | 0.87 | MEN1 (0.40) | MAPTKDM4EALDH1A1AKR1C3HTT | |
| SCHEMBL5551024 | 0.86 | KMT2A (0.42) | MAPTKDM4EALDH1A1HTTMEN1 | |
| SCHEMBL1845080 | 0.85 | KEAP1 (0.38) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1845591 | 0.85 | KDM4E (0.43) | SLC16A3MAPTKDM4EALDH1A1AKR1C3 | |
| SCHEMBL5550214 | 0.84 | KMT2A (0.47) | MAPTKDM4EALDH1A1AKR1C3HTT | |
| SCHEMBL8509702 | 0.83 | MEN1 (0.43) | SLC16A3MAPTKDM4EALDH1A1AKR1C3 | |
| SCHEMBL5649476 | 0.83 | RAB9A (0.39) | MAPTKDM4EALDH1A1AKR1C3MEN1 | |
| SCHEMBL5550993 | 0.81 | MAPT (0.38) | MAPTKDM4EALDH1A1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248264-B1 | WINDOWS OR EYEGLASS/SUNGLASS LENSES HAVING GOOD DARKENING AND LIGHTENING PERFORMANCE WITH HIGH OPTICAL DENSITY | JAMES ROBINSON LIMITED (GB) | 2001-06-19 | — | — | US | disclosed |
| EP-0971914-A2 | NEUTRAL COLOURING PHOTOCHROMIC 2$i(H)-NAPHTHO 1,2-$i(b)]PYRANS AND HETEROCYCLIC PYRANS | JAMES ROBINSON LIMITED (GB) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998042693-A2 | NEUTRAL COLOURING PHOTOCHROMIC 2H-NAPHTHO[1,2-b]PYRANS AND HETEROCYCLIC PYRANS | JAMES ROBINSON LIMITED (GB) | 1998-10-01 | — | — | WO | disclosed |