SCHEMBL18459652

SCHEMBL18459652

Cc1nc(I)c(-c2ccccc2)c2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.48
MAPT P10636 4/20 0.41
GAA P10253 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
SMN1; SMN2 Q16637 5/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
BRD4 O60885 2/20 0.40
CHEK1 O14757 1/20 0.40
AKT2 P31751 1/20 0.40
BRD2 P25440 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP1A2 P05177 1/20 0.40
HPGD P15428 1/20 0.40
NUDT1 P36639 1/20 0.40
HSD17B10 Q99714 1/20 0.40
TDO2 P48775 1/20 0.38
NPC1 O15118 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16352606 0.82 GPR3 (0.54) GPR3MAPTGAANPSR1SMN1; SMN2
SCHEMBL28183986 0.78 GPR3 (0.50) GPR3MAPTGAANPSR1SMN1; SMN2
SCHEMBL2264181 0.77 KDM4E (0.62) GPR3MAPTGAANPSR1SMN1; SMN2
SCHEMBL18799925 0.75 GPR3 (0.50) GPR3MAPTSMN1; SMN2L3MBTL1KDM4E
SCHEMBL13379991 0.73 HSD17B10 (0.46) GPR3MAPTGAANPSR1KDM4E
SCHEMBL29101891 0.72 GPR3 (0.43) GPR3MAPTGAANPSR1SMN1; SMN2
SCHEMBL36757 0.68 ACHE (0.56) MAPTL3MBTL1KDM4EMAPK1TDP1
SCHEMBL29354925 0.68 ACHE (0.56) MAPTL3MBTL1KDM4EMAPK1TDP1
SCHEMBL5434073 0.68 MAPT (0.60) GPR3MAPTGAANPSR1SMN1; SMN2
SCHEMBL16189083 0.68 LMNA (0.49) MAPTGAANPSR1SMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11653563-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-16 US disclosed
US-11552260-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-01-10 US disclosed
US-11538999-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2022-12-27 US disclosed
US-11276827-B2 Condensed cyclic compound and an organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2022-03-15 US disclosed
US-11050027-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-06-29 US disclosed
US-11038113-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2021-06-15 US disclosed
US-10916708-B2 Condensed cyclic compound and organic light emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2021-02-09 US disclosed
US-10818851-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-10-27 US disclosed
US-10727417-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-28 US disclosed
US-10461263-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-10-29 US disclosed
US-9711736-B2 Condensed cyclic compound and organic light-emitting device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-18 US disclosed
US-20170200905-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-13 US disclosed
US-9705088-B2 Triazine-based compounds and organic light-emitting devices including triazine-based compounds SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-11 US disclosed
US-20170179404-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed
US-20170170404-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-15 US disclosed
US-9673400-B2 Amine-based compound and organic light-emitting diode including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-06 US disclosed
US-9660204-B2 Silane-based compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-05-23 US disclosed
US-20170104166-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-04-13 US disclosed
US-20170069847-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Research & Business Foundation Sungkyunkwan University (KR) 2017-03-09 US disclosed
US-20170033297-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170200905-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNA1 GPR3 3219/4885MAPT 1538/4885GAA 3821/4885
US-20170179404-A1 ORGANIC LIGHT-EMITTING DEVICE OR51E2, OCIAD1, OXA1L GPR3 2846/4885MAPT 2225/4885GAA 3244/4885
US-10916708-B2 Condensed cyclic compound and organic light emitting device including the same C1S, C9, CCNT1 GPR3 1601/4885MAPT 3229/4885GAA 4504/4885
US-11538999-B2 Heterocyclic compound and organic light-emitting device including the same CCNT1, CYP1A1, CRY1 GPR3 2418/4885MAPT 1593/4885GAA 2397/4885
US-10461263-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CCNA1, CCNE2 GPR3 3337/4885MAPT 1063/4885GAA 3565/4885
US-11050027-B2 Condensed cyclic compound and organic light-emitting device including the same CCNT1, CRY1, CCNA1 GPR3 3098/4885MAPT 1657/4885GAA 3791/4885
US-11276827-B2 Condensed cyclic compound and an organic light-emitting device including the same CRY1, CRY2, CCNA1 GPR3 3219/4885MAPT 1538/4885GAA 3821/4885
US-20170104166-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 GPR3 4044/4885MAPT 1556/4885GAA 3750/4885
US-20170033297-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CCNE2, CCNE1, CCNA1 GPR3 3551/4885MAPT 1653/4885GAA 3304/4885
US-10818851-B2 Condensed cyclic compound and organic light-emitting device including the same CCNE2, CCNE1, CCNA1 GPR3 3551/4885MAPT 1653/4885GAA 3304/4885
US-11552260-B2 Condensed cyclic compound and organic light-emitting device including the same CCND2, CCNE2, CRY1 GPR3 1448/4885MAPT 1332/4885GAA 4461/4885
US-20170069847-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 GPR3 3095/4885MAPT 1050/4885GAA 4045/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.