SCHEMBL18489488

SCHEMBL18489488

CC(C)c1cccc(C(C)C)c1N=Cc1ccc2ccccc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
KDM4E B2RXH2 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
DHODH Q02127 1/20 0.50
LMNA P02545 4/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
MAPT P10636 3/20 0.47
MAPK1 P28482 2/20 0.47
GAA P10253 1/20 0.47
THRB P10828 1/20 0.47
ALOX12 P18054 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.44
HPGD P15428 2/20 0.44
GRIN2D O15399 2/20 0.44
GRIN3B O60391 2/20 0.44
GRIN1 Q05586 2/20 0.44
GRIN2A Q12879 2/20 0.44
GRIN2B Q13224 2/20 0.44
GRIN2C Q14957 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18489487 1.00 ALDH1A1 (0.50) ALDH1A1KDM4EL3MBTL1DHODHLMNA
SCHEMBL18489473 0.97 DHODH (0.48) ALDH1A1KDM4EL3MBTL1DHODHLMNA
SCHEMBL18489474 0.97 DHODH (0.48) ALDH1A1KDM4EL3MBTL1DHODHLMNA
SCHEMBL18489662 0.81 LMNA (0.41) ALDH1A1KDM4EL3MBTL1LMNAKMT2A
SCHEMBL18489664 0.81 LMNA (0.41) ALDH1A1KDM4EL3MBTL1LMNAKMT2A
SCHEMBL18489618 0.77 GAA (0.42) L3MBTL1LMNAMEN1KMT2AMAPT
SCHEMBL27540015 0.77 CA2 (0.44) ALDH1A1KDM4EL3MBTL1DHODHLMNA
SCHEMBL12379905 0.76 AMY1A (0.43) ALDH1A1KDM4EL3MBTL1LMNAMEN1
SCHEMBL23644508 0.75 CA2 (0.44) LMNAMEN1KMT2AMAPTGAA
SCHEMBL18489538 0.75 CA2 (0.44) LMNAMEN1KMT2AMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3135699-B1 CATALYST COMPONENT FOR PROPYLENE POLYMERIZATION, PREPARATION METHOD THEREFOR AND CATALYST HAVING SAME CHINA PETROLEUM & CHEM CORP (CN) 2021-07-21 EP claimed
US-10184017-B2 Catalyst component for propene polymerization, preparation method thereof, and catalyst containing the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-01-22 US claimed
EP-3135699-A1 CATALYST COMPONENT FOR PROPYLENE POLYMERIZATION, PREPARATION METHOD THEREFOR AND CATALYST HAVING SAME China Petroleum & Chemical Corporation (CN) 2017-03-01 EP claimed
US-20170044280-A1 Catalyst Component for Propene Polymerization, Preparation Method Thereof, and Catalyst Containing the Same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2017-02-16 US claimed
EP-3135699-B1 CATALYST COMPONENT FOR PROPYLENE POLYMERIZATION, PREPARATION METHOD THEREFOR AND CATALYST HAVING SAME CHINA PETROLEUM & CHEM CORP (CN) 2021-07-21 EP disclosed
US-10184017-B2 Catalyst component for propene polymerization, preparation method thereof, and catalyst containing the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-01-22 US disclosed
EP-3135699-A1 CATALYST COMPONENT FOR PROPYLENE POLYMERIZATION, PREPARATION METHOD THEREFOR AND CATALYST HAVING SAME China Petroleum & Chemical Corporation (CN) 2017-03-01 EP disclosed
US-20170044280-A1 Catalyst Component for Propene Polymerization, Preparation Method Thereof, and Catalyst Containing the Same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2017-02-16 US disclosed