Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSH | P09668 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | GRN | P28799 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18494009 | 0.90 | CTSL (0.39) | CTSLCTSBCTSHCTSKMMP1 | |
| SCHEMBL13710937 | 0.86 | CTSK (0.42) | CTSLCTSBCTSHCTSKMMP1 | |
| SCHEMBL13711061 | 0.86 | CTSK (0.42) | CTSLCTSBCTSHCTSKMMP1 | |
| SCHEMBL3617417 | 0.86 | CTSK (0.42) | CTSLCTSBCTSHCTSKMMP1 | |
| SCHEMBL18435239 | 0.81 | CTSK (0.44) | CTSLCTSBCTSHCTSKMMP1 | |
| SCHEMBL13707911 | 0.81 | CTSK (0.44) | CTSLCTSBCTSHCTSKMMP1 | |
| SCHEMBL13707910 | 0.81 | CTSK (0.44) | CTSLCTSBCTSHCTSKMMP1 | |
| SCHEMBL31252283 | 0.79 | CTSK (0.40) | CTSLCTSBCTSHCTSKLTA4H | |
| SCHEMBL8337764 | 0.79 | GRN (0.46) | CTSLCTSBCTSKMMP1MMP2 | |
| SCHEMBL18120817 | 0.78 | CPB2 (0.45) | CTSLCTSBCTSHCTSKMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170037086-A1 | PEPTIDOMIMETIC MACROCYCLES WITH PTH ACTIVITY | AILERON THERAPEUTICS, INC. | 2017-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170037086-A1 | PEPTIDOMIMETIC MACROCYCLES WITH PTH ACTIVITY | PTH1R, CALCA, CALCB | CTSL 181/4885CTSB 305/4885CTSH 237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.