Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 5/20 | 0.46 |
| ▸ | AURKA | O14965 | 2/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29992620 | 0.80 | PARP1 (0.65) | MAPTGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL12590230 | 0.80 | MAPK14 (0.36) | CHEK1MAPK14GRM4METAP2METAP1 | |
| SCHEMBL1847464 | 0.80 | PARP1 (0.65) | MAPTGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL12590239 | 0.79 | GRM4 (0.48) | MAPTGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL473671 | 0.77 | CHUK (0.63) | MAPTGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL12590234 | 0.77 | CHUK (0.53) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL12590228 | 0.77 | GABRA1 (0.47) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL2391060 | 0.77 | GABRA1 (0.53) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL31485825 | 0.77 | CHUK (0.63) | MAPTGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL29475851 | 0.77 | CHUK (0.63) | MAPTGABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9419231-B2 | Organic electroluminescence device | IDEMITSU KOSAN CO., LTD. (JP) | 2016-08-16 | — | — | US | disclosed |
| US-9419231-B2 | Organic electroluminescence device | IDEMITSU KOSAN CO., LTD. (JP) | 2016-08-16 | — | — | US | disclosed |
| US-20150368244-A1 | DIAZACARBAZOLES AND METHODS OF USE | GENENTECH, INC. (US) | 2015-12-24 | — | — | US | disclosed |
| US-20140027744-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2014-01-30 | — | — | US | disclosed |
| US-20140027744-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2014-01-30 | — | — | US | disclosed |
| EP-2324024-B1 | DIAZACARBAZOLES AND METHODS OF USE | GENENTECH INC (US) | 2012-09-26 | — | — | EP | disclosed |
| US-7968213-B2 | Material for organic electroluminescence device and organic electroluminescence device utilizing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-06-28 | — | — | US | disclosed |
| US-7968213-B2 | Material for organic electroluminescence device and organic electroluminescence device utilizing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-06-28 | — | — | US | disclosed |
| US-20110124654-A1 | DIAZACARBAZOLES AND METHODS OF USE | ARGENTA DISCOVERY 2009 LIMITED (GB) | 2011-05-26 | — | — | US | disclosed |
| EP-2324024-A1 | DIAZACARBAZOLES AND METHODS OF USE | Genentech, Inc. (US) | 2011-05-25 | — | — | EP | disclosed |
| WO-2009151589-A1 | DIAZACARBAZOLES AND METHODS OF USE | GENENTECH, INC. (US) | 2009-12-17 | — | — | WO | disclosed |
| US-20090017331-A1 | MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2009-01-15 | — | — | US | disclosed |
| US-20090017331-A1 | MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124654-A1 | DIAZACARBAZOLES AND METHODS OF USE | CHEK1, CHEK2, BUB1B | MAPT 4332/4885GABRA1 1725/4885GABRG2 1785/4885 |
| US-20090017331-A1 | MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME | ICMT, ORAI2, ILK | MAPT 234/4885GABRA1 4577/4885GABRG2 4575/4885 |
| US-20150368244-A1 | DIAZACARBAZOLES AND METHODS OF USE | CHEK1, CHEK2, BUB1B | MAPT 4332/4885GABRA1 1725/4885GABRG2 1785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.