SCHEMBL822668

SCHEMBL822668

O=C(O)c1ccc(C(=O)NCCc2ccccc2)c2c(C(=O)O)ccc(C(=O)NCCc3ccccc3)c12

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 8/20 0.62
NPC1 O15118 8/20 0.62
MAPT P10636 2/20 0.61
LMNA P02545 1/20 0.61
SMN1; SMN2 Q16637 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
HDAC2 Q92769 1/20 0.55
HDAC8 Q9BY41 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55
CA12 O43570 2/20 0.54
CA2 P00918 2/20 0.54
CA9 Q16790 2/20 0.54
CA1 P00915 1/20 0.54
MMP1 P03956 1/20 0.54
MMP2 P08253 1/20 0.54
MMP3 P08254 1/20 0.54
EGLN1 Q9GZT9 1/20 0.53
ALDH1A1 P00352 1/20 0.53
HPGD P15428 1/20 0.53
TSHR P16473 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16352053 1.00 RAB9A (0.62) RAB9ANPC1MAPTLMNASMN1; SMN2
SCHEMBL3796253 1.00 RAB9A (0.62) RAB9ANPC1MAPTLMNASMN1; SMN2
SCHEMBL5187348 0.94 RAB9A (0.56) RAB9ANPC1MAPTLMNASMN1; SMN2
SCHEMBL16351643 0.94 RAB9A (0.56) RAB9ANPC1MAPTLMNASMN1; SMN2
SCHEMBL823219 0.94 RAB9A (0.56) RAB9ANPC1MAPTLMNASMN1; SMN2
SCHEMBL12037458 0.89 RAB9A (0.51) RAB9ANPC1MAPTLMNASMN1; SMN2
SCHEMBL5051133 0.89 KMT2A (0.56) RAB9ANPC1MAPTLMNASMN1; SMN2
SCHEMBL823212 0.89 RAB9A (0.51) RAB9ANPC1MAPTLMNASMN1; SMN2
SCHEMBL12037456 0.89 RAB9A (0.51) RAB9ANPC1MAPTLMNASMN1; SMN2
SCHEMBL16351287 0.89 PLAAT3 (0.52) RAB9ANPC1MAPTLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530270-B2 Methods of preparing semiconductive compositions and devices EASTMAN KODAK COMPANY (US) 2013-09-10 US disclosed
US-8530270-B2 Methods of preparing semiconductive compositions and devices EASTMAN KODAK COMPANY (US) 2013-09-10 US disclosed
US-8431433-B2 Methods of providing semiconductor layers from amic acid salts EASTMAN KODAK COMPANY (US) 2013-04-30 US disclosed
US-8411489-B2 Semiconducting devices and methods of preparing EASTMAN KODAK COMPANY (US) 2013-04-02 US disclosed
US-8411489-B2 Semiconducting devices and methods of preparing EASTMAN KODAK COMPANY (US) 2013-04-02 US disclosed
US-8314265-B2 Aromatic amic acids or amic esters and compositions EASTMAN KODAK COMPANY (US) 2012-11-20 US disclosed
US-8314265-B2 Aromatic amic acids or amic esters and compositions EASTMAN KODAK COMPANY (US) 2012-11-20 US disclosed
US-20110295010-A1 AROMATIC AMIC ACID SALTS AND COMPOSITIONS FPC INC. 2011-12-01 US disclosed
WO-2011137139-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS EASTMAN KODAK COMPANY (US) 2011-11-03 WO disclosed
US-20110269967-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS BANK OF AMERICA, N.A., AS AGENT 2011-11-03 US disclosed
US-20110269967-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS BANK OF AMERICA, N.A., AS AGENT 2011-11-03 US disclosed
WO-2011137133-A2 SEMICONDUCTING DEVICES AND METHODS OF PREPARING EASTMAN KODAK COMPANY (US) 2011-11-03 WO disclosed
WO-2011137137-A1 SEMICONDUCTING ARTICLES EASTMAN KODAK COMPANY (US) 2011-11-03 WO disclosed
US-20110269265-A1 METHODS OF PREPARING SEMICONDUCTIVE COMPOSITIONS AND DEVICES KODAK REALTY INC. 2011-11-03 US disclosed
US-20110269265-A1 METHODS OF PREPARING SEMICONDUCTIVE COMPOSITIONS AND DEVICES KODAK REALTY INC. 2011-11-03 US disclosed
US-20110266523-A1 SEMICONDUCTING DEVICES AND METHODS OF PREPARING BANK OF AMERICA, N.A., AS AGENT 2011-11-03 US disclosed
US-20110266523-A1 SEMICONDUCTING DEVICES AND METHODS OF PREPARING BANK OF AMERICA, N.A., AS AGENT 2011-11-03 US disclosed
US-20110269966-A1 SEMICONDUCTING ARTICLES CITICORP NORTH AMERICA, INC., AS AGENT 2011-11-03 US disclosed
US-20110269966-A1 SEMICONDUCTING ARTICLES CITICORP NORTH AMERICA, INC., AS AGENT 2011-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295010-A1 AROMATIC AMIC ACID SALTS AND COMPOSITIONS DDC, MYOC, TNNC1 RAB9A 1098/4885NPC1 2760/4885MAPT 1430/4885
US-20110269966-A1 SEMICONDUCTING ARTICLES ALAD, PORCN, DDC RAB9A 2482/4885NPC1 2148/4885MAPT 1981/4885
US-20110269967-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS DDC, AADAC, MYOC RAB9A 1518/4885NPC1 2077/4885MAPT 1597/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.