Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 2/20 | 0.53 |
| ▸ | TDO2 | P48775 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19074303 | 0.82 | TDO2 (0.49) | BCL2TDO2KMT2ATDP1NPC1 | |
| SCHEMBL15596459 | 0.82 | ALDH1A1 (0.51) | BCL2KMT2ATDP1MEN1MAPT | |
| SCHEMBL15024758 | 0.81 | IMPDH2 (0.53) | BCL2KMT2ATDP1MEN1MAPT | |
| SCHEMBL1849779 | 0.80 | NPC1 (0.51) | BCL2TDO2KMT2ATDP1NPC1 | |
| SCHEMBL28308266 | 0.79 | MAPT (0.58) | BCL2TDO2KMT2AMEN1MAPT | |
| SCHEMBL15055546 | 0.78 | TDP1 (0.67) | KMT2ATDP1MEN1MAPTGAA | |
| SCHEMBL16582329 | 0.78 | ALDH1A1 (0.63) | KMT2ATDP1MEN1MAPTCYP1A2 | |
| SCHEMBL1202543 | 0.78 | IMPDH2 (0.63) | KMT2ATDP1MEN1MAPTCYP1A2 | |
| SCHEMBL1287837 | 0.78 | ALDH1A1 (0.74) | KMT2ATDP1NPC1MEN1CYP1A2 | |
| SCHEMBL30535903 | 0.78 | ALDH1A1 (0.74) | KMT2ATDP1NPC1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250368645-A1 | BETA CARBOLINE ANALOGUES AS SELECTIVE AND BIASED KAPPA OPIOID RECEPTORS AGONISTS FOR TREATING VARIOUS ASSOCIATED PATHOPHYSIOLOGICAL CONDITIONS | COUNCIL SCIENT IND RES (IN) | 2025-12-04 | — | — | US | disclosed |
| EP-4543880-A1 | BETA CARBOLINE ANALOGUES AS SELECTIVE AND BIASED KAPPA OPIOID RECEPTORS AGONISTS FOR TREATING VARIOUS ASSOCIATED PATHOPHYSIOLOGICAL CONDITIONS | Council Of Scientific & Industrial Research (IN) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023248255-A1 | BETA CARBOLINE ANALOGUES AS SELECTIVE AND BIASED KAPPA OPIOID RECEPTORS AGONISTS FOR TREATING VARIOUS ASSOCIATED PATHOPHYSIOLOGICAL CONDITIONS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2023-12-28 | — | — | WO | disclosed |
| CN-111269234-A | Method for synthesizing 2-aminoindolo [2,3-b ] indole derivative in one step | 华南理工大学 | 2020-06-12 | — | — | CN | disclosed |
| EP-2617724-B1 | ORGANIC ELECTROLUMINESCENT DEVICE | NIPPON STEEL & SUMIKIN CHEM CO (JP) | 2017-07-05 | — | — | EP | disclosed |
| EP-2628743-B1 | NITROGENATED AROMATIC COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC ELECTRONIC DEVICE | NIPPON STEEL & SUMIKIN CHEM CO (JP) | 2016-02-24 | — | — | EP | disclosed |
| US-8766248-B2 | Nitrogen-containing aromatic compound, organic semiconductor material, and organic electronic device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2014-07-01 | — | — | US | disclosed |
| US-8766248-B2 | Nitrogen-containing aromatic compound, organic semiconductor material, and organic electronic device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2014-07-01 | — | — | US | disclosed |
| US-8766249-B2 | Nitrogenated aromatic compound, organic semiconductor material, and organic electronic device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2014-07-01 | — | — | US | disclosed |
| US-8766249-B2 | Nitrogenated aromatic compound, organic semiconductor material, and organic electronic device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2014-07-01 | — | — | US | disclosed |
| CN-101421265-A | Thiazole compounds as protein kinase b (pkb) inhibitors | AMGEN INC (US) | 2009-04-29 | — | — | CN | disclosed |
| EP-0872903-B1 | Method for making hydrogen storage alloy powder and electrode comprising the alloy powder | SHINETSU CHEMICAL CO (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-6277519-B1 | QUENCHING AN ALLOY MELT; COMMINUTION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2001-08-21 | — | — | US | disclosed |
| US-6096144-A | TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2000-08-01 | — | — | US | disclosed |
| US-5858571-A | TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0872903-A1 | Method for making hydrogen storage alloy powder and electrode comprising the alloy powder | Shin-Etsu Chemical Co., Ltd. (JP) | 1998-10-21 | — | — | EP | disclosed |
| EP-0172427-B1 | PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER | Shin-Etsu Chemical Co., Ltd. (JP) | 1989-07-05 | — | — | EP | disclosed |
| US-4758639-A | Process for production of vinyl polymer | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-19 | — | — | US | disclosed |
| US-4757124-A | Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0172427-A2 | Process for production of vinyl chloride polymer | Shin-Etsu Chemical Co., Ltd. (JP) | 1986-02-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250368645-A1 | BETA CARBOLINE ANALOGUES AS SELECTIVE AND BIASED KAPPA OPIOID RECEPTORS AGONISTS FOR TREATING VARIOUS ASSOCIATED PATHOPHYSIOLOGICAL CONDITIONS | OPRK1, OPRD1, OPRM1 | BCL2 1122/4885TDO2 963/4885KMT2A 1088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.