Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.68 |
| ▸ | RAD52 | P43351 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MET | P08581 | 1/20 | 0.51 |
| ▸ | SMO | Q99835 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6257685 | 0.84 | ALDH1A1 (0.53) | GPR84RAB9AALDH1A1POLBKMT2A | |
| SCHEMBL2028344 | 0.82 | GPR84 (1.00) | GPR84NPC1RAB9AALDH1A1PBRM1 | |
| SCHEMBL975117 | 0.80 | ALDH1A1 (0.68) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL8793654 | 0.78 | MET (0.66) | GPR84NPC1RAB9AALDH1A1PBRM1 | |
| SCHEMBL9334168 | 0.77 | GPR84 (0.59) | GPR84NPC1RAB9AALDH1A1PBRM1 | |
| SCHEMBL9208355 | 0.76 | GPR84 (0.79) | GPR84NPC1RAB9AALDH1A1PBRM1 | |
| SCHEMBL10645520 | 0.76 | GPR84 (0.79) | GPR84RAB9AALDH1A1PBRM1ATM | |
| SCHEMBL28129599 | 0.76 | GPR84 (0.79) | GPR84NPC1RAB9AALDH1A1PBRM1 | |
| SCHEMBL29567770 | 0.76 | GPR84 (0.57) | GPR84NPC1RAB9AMETSMO | |
| SCHEMBL1849779 | 0.76 | NPC1 (0.51) | GPR84RAD52NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10195048-A | — | — | None | — | — | JP | disclosed |
| WO-2005000813-A1 | HETEROARYLAMINO-PHENYLKETONE DERIVATIVES AND THEIR USE AS KINASE INHIBITORS | IMCLONE SYSTEMS INCORPORATED (US) | 2005-01-06 | — | — | WO | disclosed |
| JP-H10195048-A | PRODUCTION OF 3-(NITROBENZOYL) INDOLE DERIVATIVE | SUMITOMO CHEM CO LTD | 1998-07-28 | — | — | JP | disclosed |