Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2D3 | P61077 | 2/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 9/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17214373 | 0.90 | UBE2D3 (0.37) | UBE2D3NLRP3PKMABCB1 | |
| SCHEMBL17214372 | 0.77 | PKM (0.36) | UBE2D3NLRP3PKM | |
| SCHEMBL18506553 | 0.59 | PKM (0.34) | UBE2D3NLRP3PKM | |
| SCHEMBL17214363 | 0.58 | PKM (0.38) | NLRP3PKM | |
| SCHEMBL18501586 | 0.58 | PKM (0.38) | NLRP3PKM | |
| Dehydrocostuslactone SCHEMBL936050 | 0.56 | CYP19A1 (0.46) | NLRP3PKM | |
| SCHEMBL18501587 | 0.56 | PKM (0.38) | NLRP3PKM | |
| Dehydrozaluzanin C SCHEMBL17214360 | 0.55 | CYP19A1 (0.42) | NLRP3PKM | |
| SCHEMBL1426503 | 0.55 | GAA (0.49) | — | |
| SCHEMBL22305507 | 0.54 | PKM (0.41) | UBE2D3NLRP3PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670226-B2 | Sesquiterpenoids | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2017-06-06 | — | — | US | disclosed |
| US-9670226-B2 | Sesquiterpenoids | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2017-06-06 | — | — | US | disclosed |
| US-20170044180-A1 | Sesquiterpenoids | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2017-02-16 | — | — | US | disclosed |
| US-20170044180-A1 | Sesquiterpenoids | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044180-A1 | Sesquiterpenoids | NFKBIA, RELA, IKBKG | UBE2D3 954/4885NLRP3 192/4885OPRM1 4025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.