Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 4/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18503613 | 0.92 | POLB (0.43) | POLBMAPTPTGESKCNH2SCN5A | |
| SCHEMBL18503586 | 0.90 | PTGES (0.39) | POLBMAPTPTGESSCN9AABL1 | |
| SCHEMBL18503597 | 0.90 | POLB (0.42) | POLBMAPTPTGESKCNH2SCN5A | |
| SCHEMBL16771948 | 0.88 | AKR1C3 (0.41) | POLBPTGESP2RX7 | |
| SCHEMBL16760327 | 0.87 | P2RX7 (0.40) | POLBPTGESP2RX7 | |
| SCHEMBL18503588 | 0.87 | P2RX7 (0.46) | P2RX7 | |
| SCHEMBL18503633 | 0.85 | PTGES (0.38) | POLBMAPTPTGESKCNH2SCN5A | |
| SCHEMBL18503625 | 0.83 | CHRM3 (0.40) | PTGESSCN5ASCN9AP2RX7 | |
| SCHEMBL19566578 | 0.83 | ROCK2 (0.41) | MAPTPTGESSCN9AP2RX7 | |
| SCHEMBL19566547 | 0.83 | CHRM3 (0.45) | POLBMAPTPTGESP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044104-A1 | NEW PESTICIDAL COMPOUNDS AND USES | BAYER ANIMAL HEALTH GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
| US-20170044104-A1 | NEW PESTICIDAL COMPOUNDS AND USES | BAYER ANIMAL HEALTH GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044104-A1 | NEW PESTICIDAL COMPOUNDS AND USES | ACHE, DDT, DNPH1 | POLB 4640/4885MAPT 3764/4885PTGES 679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.