Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19566553 | 0.93 | HDAC6 (0.44) | HDAC6CNR2GRM4LMNAP2RX7 | |
| SCHEMBL19566560 | 0.92 | HDAC6 (0.45) | HDAC6SCN2ASCN10AKCNH2SCN5A | |
| SCHEMBL16212574 | 0.92 | HDAC6 (0.48) | HDAC6CNR2KDM4EHPGDGRM4 | |
| SCHEMBL19566563 | 0.91 | HDAC6 (0.44) | HDAC6SCN2ASCN10AKCNH2SCN5A | |
| SCHEMBL16771887 | 0.89 | HDAC6 (0.43) | HDAC6MCHR1CNR2GRM4P2RX7 | |
| SCHEMBL18503592 | 0.88 | HDAC6 (0.42) | HDAC6CNR2GRM4P2RX7CYP1A2 | |
| SCHEMBL19566550 | 0.84 | P2RX7 (0.47) | KDM4EHPGDLIPGLMNAPOLB | |
| SCHEMBL16211922 | 0.82 | HDAC6 (0.55) | HDAC6MCHR1CNR2HPGDALDH1A1 | |
| SCHEMBL17713159 | 0.82 | HDAC6 (0.46) | HDAC6CNR2LMNACYP1A2CYP2C9 | |
| SCHEMBL19566561 | 0.82 | HDAC6 (0.46) | HDAC6CNR2LMNACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170320848-A1 | COMPOUNDS FOR USE IN ANTHELMINTHIC TREATMENT | BAYER ANIMAL HEALTH GMBH (DE) | 2017-11-09 | — | — | US | disclosed |
| US-20170320848-A1 | COMPOUNDS FOR USE IN ANTHELMINTHIC TREATMENT | BAYER ANIMAL HEALTH GMBH (DE) | 2017-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170320848-A1 | COMPOUNDS FOR USE IN ANTHELMINTHIC TREATMENT | ACHE, COX5B, TUBB6 | HDAC6 278/4885SCN2A 1993/4885SCN10A 2144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.