Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 7/20 | 0.60 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.60 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18503608 | 0.93 | CYP11B1 (0.51) | CYP11B2CYP11B1DGAT2PIK3CAPIK3CG | |
| SCHEMBL19566551 | 0.88 | CYP11B1 (0.48) | CYP11B2CYP11B1TP53PTGESABCB1 | |
| SCHEMBL18503598 | 0.88 | CYP11B2 (0.49) | CYP11B2CYP11B1TP53PTGESHCRTR1 | |
| SCHEMBL18503595 | 0.86 | CYP11B2 (0.42) | CYP11B2CYP11B1TP53PTGESHCRTR1 | |
| SCHEMBL18503629 | 0.85 | LMNA (0.41) | CYP11B2CYP11B1TP53PTGESHCRTR1 | |
| SCHEMBL18503600 | 0.84 | KIF11 (0.44) | CYP11B2CYP11B1PIK3CGTP53HCRTR1 | |
| SCHEMBL18503597 | 0.84 | POLB (0.42) | CYP11B2CYP11B1SLC22A12TP53PTGES | |
| SCHEMBL18503604 | 0.83 | CYP11B2 (0.44) | CYP11B2CYP11B1PIK3CATP53HCRTR1 | |
| SCHEMBL17713105 | 0.81 | TP53 (0.48) | TP53 | |
| SCHEMBL18503603 | 0.81 | ROCK1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044104-A1 | NEW PESTICIDAL COMPOUNDS AND USES | BAYER ANIMAL HEALTH GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
| US-20170044104-A1 | NEW PESTICIDAL COMPOUNDS AND USES | BAYER ANIMAL HEALTH GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044104-A1 | NEW PESTICIDAL COMPOUNDS AND USES | ACHE, DDT, DNPH1 | CYP11B2 2963/4885CYP11B1 3138/4885DGAT2 1612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.