Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5905873 | 0.85 | CYP1A2 (0.42) | CYP1A2L3MBTL1ALDH1A1KMT2AHTT | |
| SCHEMBL18503960 | 0.84 | MAPT (0.48) | CYP1A2RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL18504314 | 0.84 | NOTUM (0.43) | CYP1A2L3MBTL1KMT2AHTTNOTUM | |
| SCHEMBL8600506 | 0.83 | MGLL (0.49) | RAB9AALDH1A1MGLLNPC1NTRK1 | |
| SCHEMBL8598461 | 0.82 | L3MBTL1 (0.48) | CYP1A2L3MBTL1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5905967 | 0.81 | CYP1A2 (0.48) | CYP1A2L3MBTL1RAB9AALDH1A1MAPT | |
| SCHEMBL5906182 | 0.81 | RXRA (0.40) | CYP1A2L3MBTL1 | |
| SCHEMBL5906108 | 0.81 | PIM1 (0.43) | L3MBTL1HTTNOTUM | |
| SCHEMBL22563818 | 0.81 | CYP1A2 (0.37) | CYP1A2L3MBTL1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3239509 | 0.79 | IDO1 (0.46) | CYP1A2ALDH1A1HTTMGLLNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113301901-B | Tetrazolinone substituted steroids and uses thereof | 北京轩义医药科技有限公司 | 2022-09-09 | — | — | CN | disclosed |
| US-20220089636-A1 | TETRAZOLONE SUBSTITUTED STEROIDS AND USE THEREOF | BEIJING XUANYI PHARMASCIENCES CO., LTD. (CN) | 2022-03-24 | — | — | US | disclosed |
| EP-3911331-A1 | TETRAZOLONE SUBSTITUTED STEROIDS AND USE THEREOF | Beijing Xuanyi Pharmasciences Co., Ltd. (CN) | 2021-11-24 | — | — | EP | disclosed |
| CN-113301901-A | Tetrazolinone substituted steroids and uses thereof | 北京轩义医药科技有限公司 | 2021-08-24 | — | — | CN | disclosed |
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |
| WO-2020150210-A1 | TETRAZOLONE SUBSTITUTED STEROIDS AND USE THEREOF | BEIJING XUANYI PHARMASCIENCES CO., LTD. (CN) | 2020-07-23 | — | — | WO | disclosed |
| WO-2020150210-A1 | TETRAZOLONE SUBSTITUTED STEROIDS AND USE THEREOF | BEIJING XUANYI PHARMASCIENCES CO., LTD. (CN) | 2020-07-23 | — | — | WO | disclosed |
| US-9565856-B2 | Tetrazolinone compounds and its use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-14 | — | — | US | disclosed |
| CN-1104639-A | A process for the preparation of 1-substituted-5(4H)-tetrazolinones | BAYER AGROCHEM KK (JP) | 1995-07-05 | — | — | CN | disclosed |
| CN-1102183-A | Process for the preparation of 1,4-disubstituted-5(4H)-tetrazolinones | BAYER AGROCHEM KK (JP) | 1995-05-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220089636-A1 | TETRAZOLONE SUBSTITUTED STEROIDS AND USE THEREOF | CACNA1I, TAAR5, TAAR1 | CYP1A2 189/4885L3MBTL1 2698/4885RAB9A 610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.