Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | MMP1 | P03956 | 3/20 | 0.53 |
| ▸ | MMP3 | P08254 | 2/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 4/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 4/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.52 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 7/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18506558 | 1.00 | L3MBTL1 (0.67) | L3MBTL1POLBHDAC3HDAC4HDAC1 | |
| SCHEMBL23154665 | 0.94 | L3MBTL1 (0.65) | L3MBTL1POLBHDAC3HDAC4HDAC1 | |
| SCHEMBL23154817 | 0.94 | L3MBTL1 (0.65) | L3MBTL1POLBHDAC3HDAC4HDAC1 | |
| SCHEMBL23154816 | 0.94 | L3MBTL1 (0.65) | L3MBTL1POLBHDAC3HDAC4HDAC1 | |
| SCHEMBL13063742 | 0.86 | CTSS (0.70) | L3MBTL1POLBHDAC3HDAC4HDAC1 | |
| SCHEMBL23154438 | 0.84 | L3MBTL1 (0.68) | L3MBTL1POLBHDAC3HDAC4HDAC1 | |
| SCHEMBL19361059 | 0.84 | MMP1 (0.64) | MMP1MMP3MMP8MMP2 | |
| SCHEMBL22962378 | 0.84 | MMP1 (0.64) | MMP1MMP3MMP8MMP2 | |
| SCHEMBL988137 | 0.83 | CHRNB2 (0.71) | L3MBTL1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL13778778 | 0.83 | NAAA (0.58) | L3MBTL1MMP1MMP3CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3331937-B1 | CROSS-LINKED STAR-SHAPED SELF-ASSEMBLED POLYPEPTIDES AND ITS USE AS CARRIERS IN BIOMEDICAL APPLICATIONS | CENTRO DE INVESTIG PRINCIPE FELIPE (ES) | 2019-06-19 | — | — | EP | disclosed |
| WO-2017025298-A1 | CROSS-LINKED STAR-SHAPED SELF-ASSEMBLED POLYPEPTIDES AND ITS USE AS CARRIERS IN BIOMEDICAL APPLICATIONS | CENTRO DE INVESTIGACION PRINCIPE FELIPE (ES) | 2017-02-16 | — | — | WO | disclosed |