Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA1 | P02708 | 4/20 | 0.50 |
| ▸ | CHRNG | P07510 | 4/20 | 0.50 |
| ▸ | CHRNB1 | P11230 | 4/20 | 0.50 |
| ▸ | CHRND | Q07001 | 4/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16485401 | 0.86 | CHRNB2 (0.62) | CHRNA1CHRNGCHRNB1CHRNDCHRNB2 | |
| SCHEMBL17178196 | 0.86 | CHRNB2 (0.53) | CHRNA1CHRNGCHRNB1CHRNDCHRNB2 | |
| SCHEMBL16485174 | 0.84 | CHRNB2 (0.52) | CHRNA1CHRNGCHRNB1CHRNDCHRNB2 | |
| SCHEMBL20880553 | 0.83 | CHRNB2 (0.49) | CHRNA1CHRNGCHRNB1CHRNDCHRNB2 | |
| SCHEMBL16867578 | 0.82 | QRFPR (0.53) | CHRNA1CHRNGCHRNB1CHRNDCHRNB2 | |
| SCHEMBL18515674 | 0.82 | QRFPR (0.53) | CHRNA1CHRNGCHRNB1CHRNDCHRNB2 | |
| SCHEMBL30805357 | 0.82 | CTSL (0.51) | CHRNA1CHRNGCHRNB1CHRNDCTSL | |
| SCHEMBL29385523 | 0.82 | CTSL (0.51) | CHRNA1CHRNGCHRNB1CHRNDCTSL | |
| SCHEMBL18515825 | 0.81 | CHRNB2 (0.53) | CHRNA1CHRNGCHRNB1CHRNDCHRNB2 | |
| SCHEMBL30439820 | 0.81 | OPRD1 (0.52) | CTSLOPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3130608-A1 | (ANTI-HER2 ANTIBODY)-DRUG CONJUGATE | Daiichi Sankyo Co., Ltd. (JP) | 2017-02-15 | — | — | EP | disclosed |