SCHEMBL18516993

SCHEMBL18516993

Cc1cc(C2C(=O)Oc3c2cc(C(C)(C)C)cc3C(C)(C)C)cc(C)c1OP(=O)(Oc1c(C)cc(C2C(=O)Oc3c2cc(C(C)(C)C)cc3C(C)(C)C)cc1C)Oc1c(C)cc(C2C(=O)Oc3c2cc(C(C)(C)C)cc3C(C)(C)C)cc1C

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GABBR2 O75899 1/20 0.34
GABBR1 Q9UBS5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20631181 0.92 MAPT (0.32) GABBR2GABBR1
SCHEMBL20630679 0.92 GAA (0.32) GABBR2GABBR1
SCHEMBL2612434 0.87 GABBR2 (0.36) GABBR2GABBR1
SCHEMBL21610912 0.86 GABBR2 (0.36) GABBR2GABBR1
SCHEMBL23071656 0.85 GABBR2 (0.35) GABBR2GABBR1
SCHEMBL22068544 0.85 GABBR2 (0.35) GABBR2GABBR1
SCHEMBL17021489 0.85 GABBR2 (0.35) GABBR2GABBR1
SCHEMBL5083915 0.84 GABBR2 (0.39) GABBR2GABBR1
SCHEMBL13599675 0.84 GABBR2 (0.34) GABBR2GABBR1
SCHEMBL39102 0.83 GABBR2 (0.36) GABBR2GABBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10941285-B2 Stabilized polyolefin compositions comprising benzofuranones and acid scavengers BASF SE (DE) 2021-03-09 US disclosed
US-10934423-B2 Stabilized polyolefin compositions comprising benzofuranones and organophosphorus stabilizers BASF SE (DE) 2021-03-02 US disclosed
US-10913841-B2 Stabilized polyolefin compositions comprising benzofuranones and hindered phenolic antioxidants BASF SE (DE) 2021-02-09 US disclosed
US-20200216638-A1 Stabilized Polyolefin Compositions Comprising Benzofuranones and Hindered Amine Light Stabilizers BASF SCHWEIZ AG (CH) 2020-07-09 US disclosed
US-20200181364-A1 Stabilized Polyolefin Compositions Comprising Benzofuranones and Acid Scavengers BASF SCHWEIZ AG (CH) 2020-06-11 US disclosed
EP-3334780-B1 3-PHENYL-BENZOFURAN-2-ONE DERIVATIVES CONTAINING PHOSPHORUS AS STABILIZERS BASF SE (DE) 2020-06-03 EP disclosed
WO-2019010176-A1 STABILIZED POLYOLEFIN COMPOSITIONS COMPRISING BENZOFURANONES AND HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2019-01-10 WO disclosed
WO-2019010166-A1 STABILIZED POLYOLEFIN COMPOSITIONS COMPRISING BENZOFURANONES AND ORGANOPHOSPHORUS STABILIZERS BASF SE (DE) 2019-01-10 WO disclosed
WO-2019010170-A1 STABILIZED POLYOLEFIN COMPOSITIONS COMPRISING BENZOFURANONES AND ACID SCAVENGERS BASF SE (DE) 2019-01-10 WO disclosed
WO-2019010167-A1 STABILIZED POLYOLEFIN COMPOSITIONS COMPRISING BENZOFURANONES AND HINDERED PHENOLIC ANTIOXIDANTS BASF SE (DE) 2019-01-10 WO disclosed
WO-2017025431-A1 3-PHENYL-BENZOFURAN-2-ONE DERIVATIVES CONTAINING PHOSPHORUS AS STABILIZERS BASF SE (DE) 2017-02-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10941285-B2 Stabilized polyolefin compositions comprising benzofuranones and acid scavengers PUF60, PCBP1, MORF4L1 GABBR2 1285/4885GABBR1 1099/4885
US-10913841-B2 Stabilized polyolefin compositions comprising benzofuranones and hindered phenolic antioxidants PUF60, GPX4, BPTF GABBR2 3048/4885GABBR1 2779/4885
US-10934423-B2 Stabilized polyolefin compositions comprising benzofuranones and organophosphorus stabilizers PUF60, MORF4L1, BRPF1 GABBR2 351/4885GABBR1 256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.