SCHEMBL94358

SCHEMBL94358

N#Cc1c[nH]c2nc(N)[nH]c(=O)c12

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHUK O15111 14/20 0.56
TYMS P04818 1/20 0.48
LRRK2 Q5S007 1/20 0.46
IKBKB O14920 3/20 0.45
DPYD Q12882 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26232174 0.81 CHUK (0.49) CHUKLRRK2IKBKBDPYD
SCHEMBL18520454 0.76 DYRK1A (0.47) TYMS
SCHEMBL15061831 0.75 TYMS (0.48) TYMS
SCHEMBL12820951 0.75 DYRK1A (0.46) TYMS
SCHEMBL12884842 0.75 TYMS (0.46) TYMS
SCHEMBL24704369 0.75 DYRK1A (0.46) TYMS
SCHEMBL21161374 0.72 TYMS (0.49) TYMS
SCHEMBL166747 0.72 TYMS (0.49) TYMS
SCHEMBL2261493 0.72 TYMS (0.55) TYMS
SCHEMBL6311834 0.71 CHUK (0.71) CHUKIKBKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 689 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250339475-A1 HEPATOPROTECTIVE PROBIOTIC COMPOSITIONS UNIV TEXAS (US) 2025-11-06 US claimed
EP-4600362-A1 REPORTER GENE CONSTRUCT SENSITIVE TO QUEUOSINE LEVELS Instituto Nacional de Técnica Aeroespacial "Esteban Terradas" (ES) 2025-08-13 EP claimed
WO-2025075256-A1 APPARATUS AND METHOD FOR EARLY DISEASE DETECTION BASED ON HIGH-DEPTH CELL-FREE NUCLEIC ACID SEQUENCING (주)지놈포미 2025-04-10 WO claimed
US-20250019719-A1 Purification and Purity Assessment of RNA Molecules Synthesized with Modified Nucleosides THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2025-01-16 US claimed
WO-2024102452-A1 HEPATOPROTECTIVE PROBIOTIC COMPOSITIONS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-05-16 WO claimed
CN-113881728-B Preparation method of 7-aminomethyl-7-deazaguanine (PreQ 1) 深圳瑞德林生物技术有限公司 2023-12-15 CN claimed
US-20220145308-A1 MATERIALS AND METHODS FOR REDUCING NUCLEIC ACID DEGRADATION IN BACTERIA NATIONAL INSTITUTES OF HEALTH 2022-05-12 US claimed
US-20220096574-A1 METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING CENTRAL NERVOUS SYSTEM DISORDERS AND OTHER CONDITIONS CAUSED BY GUT MICROBIAL DYSBIOSIS HOLOBIOME, INC. (US) 2022-03-31 US claimed
WO-2021030666-A1 BASE EDITING BY TRANSGLYCOSYLATION THE BROAD INSTITUTE, INC. (US) 2021-02-18 WO claimed
WO-2020185775-A2 MATERIALS AND METHODS FOR REDUCING NUCLEIC ACID DEGRADATION IN BACTERIA UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2020-09-17 WO claimed
US-20260146262-A1 METHODS OF LIPID NANOPARTICLE PRODUCTION IN CROSS-MIXERS MODERNATX, INC. (US) 2026-05-28 US disclosed
US-20260137630-A1 COMPOSITIONS AND METHODS FOR T CELL TARGETED DELIVERY OF THERAPEUTIC AGENTS AND ACTIVATION OF T CELLS THE TRUSTEES OF THE UNIV OF PENNSYLVANIA (US) 2026-05-21 US disclosed
US-20260139030-A1 CHIMERIC PROTEINS FOR TREATING CUTANEOUS INFLAMMATION SHATTUCK LABS INC (US) 2026-05-21 US disclosed
US-12629412-B2 Betacoronavirus mRNA vaccines MODERNATX, INC. (US) 2026-05-19 US disclosed
US-20260130985-A1 NUCLEIC ACID-BASED UNIVERSAL VACCINE AND METHODS OF USE THEREOF ADVANCED RNA VACCINE ARV TECH INC (US) 2026-05-14 US disclosed
WO-2008116223-A1 PREQ1 RIBOSWITCHES AND METHODS AND COMPOSITIONS FOR USE OF AND WITH PREQ1 RIBOSWITCHES YALE UNIVERSITY (US) 2008-09-25 WO disclosed
US-7364882-B1 Enzymatic reduction of a nitrile containing compound to the corresponding amine STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY (US) 2008-04-29 US disclosed
EP-0075881-B1 7-DEAZAPURINE DERIVATIVES Takeda Chemical Industries, Ltd. (JP) 1985-02-13 EP disclosed
US-4435570-A ANTITUMOR AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1984-03-06 US disclosed
EP-0075881-A1 7-Deazapurine derivatives Takeda Chemical Industries, Ltd. (JP) 1983-04-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137630-A1 COMPOSITIONS AND METHODS FOR T CELL TARGETED DELIVERY OF THERAPEUTIC AGENTS AND ACTIVATION OF T CELLS LCP2, CD47, CD4 CHUK 2653/4885TYMS 2571/4885LRRK2 3659/4885
US-12629412-B2 Betacoronavirus mRNA vaccines RNMT, RNGTT, METTL16 CHUK 4431/4885TYMS 677/4885LRRK2 3091/4885
US-20220096574-A1 METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING CENTRAL NERVOUS SYSTEM DISORDERS AND OTHER CONDITIONS CAUSED BY GUT MICROBIAL DYSBIOSIS TPH2, TPH1, HNMT CHUK 4587/4885TYMS 1256/4885LRRK2 3760/4885
US-20260146262-A1 METHODS OF LIPID NANOPARTICLE PRODUCTION IN CROSS-MIXERS ELAVL1, IGF2BP2, FUS CHUK 3232/4885TYMS 3862/4885LRRK2 2246/4885
US-20260139030-A1 CHIMERIC PROTEINS FOR TREATING CUTANEOUS INFLAMMATION TNFRSF9, CD40, TNFSF11 CHUK 2368/4885TYMS 2098/4885LRRK2 1122/4885
US-20260130985-A1 NUCLEIC ACID-BASED UNIVERSAL VACCINE AND METHODS OF USE THEREOF UPF1, NSUN2, CD4 CHUK 3044/4885TYMS 1256/4885LRRK2 3320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.