SCHEMBL18522702

SCHEMBL18522702

C=C(C)C(=O)Oc1ccc(C2=Cc3ccc(OC(=O)C(=C)C)cc3OC2O)cc1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.39
KMT2A Q03164 2/20 0.37
ATM Q13315 1/20 0.37
NFKB1 P19838 8/20 0.35
NFKB2 Q00653 8/20 0.35
RELA Q04206 8/20 0.35
CA2 P00918 1/20 0.33
CA5A P35218 1/20 0.33
HSD17B10 Q99714 1/20 0.31
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
LMNA P02545 1/20 0.30
GAA P10253 1/20 0.30
GAPDH P04406 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20342972 0.94 NFKB1 (0.40) ELANEKMT2AATMNFKB1NFKB2
SCHEMBL21475262 0.93 ELANE (0.36) ELANEKMT2AATMCA2ESR1
SCHEMBL2182312 0.88 CA2 (0.44) KMT2ANFKB1NFKB2RELACA2
SCHEMBL22842309 0.86 ELANE (0.38) ELANEKMT2AATMNFKB1NFKB2
SCHEMBL18647054 0.84 POLB (0.38) ELANEKMT2AATMCA2
SCHEMBL18869323 0.83 THRB (0.36) NFKB1NFKB2RELAESR1ESR2
SCHEMBL12413283 0.80 LMNA (0.45) KMT2ANFKB1NFKB2RELACA2
SCHEMBL18808263 0.79 NFKB1 (0.38) NFKB1NFKB2RELA
SCHEMBL22003141 0.79 POLB (0.37) ELANECA2
SCHEMBL13970428 0.77 CA2 (0.43) KMT2ANFKB1NFKB2RELACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3924447-B1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2024-01-24 EP disclosed
WO-2023198673-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2023-10-19 WO disclosed
EP-4209566-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2023-07-12 EP disclosed
EP-4209568-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2023-07-12 EP disclosed
US-11072742-B2 Liquid-crystalline media having homeotropic alignment MERCK PATENT GMBH (DE) 2021-07-27 US disclosed
WO-2020229434-A1 METHOD FOR PREPARING A LIQUID CRYSTAL-BASED SWITCHING ELEMENT MERCK PATENT GMBH (DE) 2020-11-19 WO disclosed
EP-3428246-B1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2020-04-15 EP disclosed
EP-3604481-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2020-02-05 EP disclosed
EP-3502210-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2019-06-26 EP disclosed
US-20190185754-A1 LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2019-06-20 US disclosed
EP-2985334-B1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2018-06-20 EP disclosed
EP-2848676-B1 Liquid crystal medium MERCK PATENT GMBH (DE) 2017-07-26 EP disclosed
EP-3130651-A1 LIQUID-CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2017-02-15 EP disclosed