Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 5/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NPY2R | P49146 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3279217 | 0.80 | RORC (0.50) | P2RX3RORCALDH1A1MAPTPOLB | |
| SCHEMBL3274226 | 0.79 | RORC (0.63) | P2RX3RORCALDH1A1POLBBRD4 | |
| SCHEMBL16954818 | 0.79 | ALK (0.39) | ALDH1A1MAPTLMNAPOLBALOX12 | |
| SCHEMBL13403337 | 0.78 | RORC (0.48) | P2RX3RORCALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6935704 | 0.76 | ALDH1A1 (0.41) | P2RX3ALDH1A1MAPTLMNAPOLB | |
| SCHEMBL13257964 | 0.76 | P2RX3 (0.39) | P2RX3ALDH1A1MAPTLMNAPOLB | |
| SCHEMBL27766069 | 0.76 | RORC (0.46) | P2RX3RORCALDH1A1MAPTLMNA | |
| SCHEMBL3274687 | 0.75 | CYP1A2 (0.53) | P2RX3RORCMAPTSMN1; SMN2BRD4 | |
| SCHEMBL12369333 | 0.75 | MAPT (0.34) | P2RX3RORCALDH1A1MAPTLMNA | |
| SCHEMBL340634 | 0.75 | MDM2 (0.40) | P2RX3RORCALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017025849-A1 | BICYCLIC-FUSED HETEROARYL OR ARYL COMPOUNDS | PFIZER INC. (US) | 2017-02-16 | — | — | WO | disclosed |