Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH4 | P08319 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6759876 | 0.79 | METAP1 (0.43) | METAP1HPGDCYP1A2METAP2EPHX1 | |
| SCHEMBL10607112 | 0.79 | METAP1 (0.43) | METAP1HPGDCYP1A2METAP2EPHX1 | |
| SCHEMBL515453 | 0.78 | ADH1B (0.40) | HPGDADH1BADH1CADH1AADH4 | |
| SCHEMBL15160393 | 0.77 | MAPT (0.34) | AKR1B1 | |
| SCHEMBL11773367 | 0.76 | METAP1 (0.41) | METAP1HPGDCYP1A2METAP2EPHX1 | |
| SCHEMBL11773374 | 0.76 | METAP1 (0.41) | METAP1HPGDCYP1A2METAP2EPHX1 | |
| SCHEMBL14104894 | 0.75 | METAP1 (0.52) | METAP1HPGDADH1BADH1CADH1A | |
| SCHEMBL10069252 | 0.75 | METAP1 (0.52) | METAP1HPGDADH1BADH1CADH1A | |
| SCHEMBL9668100 | 0.75 | METAP1 (0.43) | METAP1HPGDADH1BADH1CADH1A | |
| SCHEMBL2580715 | 0.75 | METAP1 (0.50) | METAP1HPGDCYP1A2METAP2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10167303-B2 | Iridium organometallic complex containing a substituted dibenzo[f,h]quinoxaline and an electronic device having an emitting layer containing the iridium complex | UDC IRELAND LIMITED (IE) | 2019-01-01 | — | — | US | disclosed |
| EP-2802594-B1 | METAL COMPLEXES WITH DIBENZO[F,H]QUINOXALINES | UDC IRELAND LTD (IE) | 2017-04-19 | — | — | EP | disclosed |
| US-20170044194-A1 | Metal Complexes with Dibenzo[f,h]quinoxalines | UDC IRELAND LTD (IE) | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10167303-B2 | Iridium organometallic complex containing a substituted dibenzo[f,h]quinoxaline and an electronic device having an emitting layer containing the iridium complex | NDUFS5, DDT, NDUFV2 | METAP1 4221/4885HPGD 454/4885ADH1B 121/4885 |
| US-20170044194-A1 | Metal Complexes with Dibenzo[f,h]quinoxalines | NDUFS2, OCIAD2, NDUFS3 | METAP1 4523/4885HPGD 490/4885ADH1B 204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.