Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 10/20 | 0.51 |
| ▸ | CA2 | P00918 | 10/20 | 0.51 |
| ▸ | CA12 | O43570 | 7/20 | 0.51 |
| ▸ | CA9 | Q16790 | 7/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | STK17B | O94768 | 1/20 | 0.43 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.43 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14485 | 0.98 | TDP1 (0.65) | TDP1MEN1GAAKMT2AMAOA | |
| Hydrochloric Acid SCHEMBL5973450 | 0.96 | TDP1 (0.62) | TDP1MEN1GAAKMT2AMAOA | |
| Ammonia Solution, Strong SCHEMBL1322321 | 0.93 | TDP1 (0.69) | TDP1MEN1GAAKMT2AMAOA | |
| Ammonia Solution, Strong SCHEMBL8503055 | 0.93 | TDP1 (0.69) | TDP1MEN1GAAKMT2AMAOA | |
| Ammonia Solution, Strong SCHEMBL5287467 | 0.93 | TDP1 (0.69) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL181700 | 0.92 | TDP1 (0.68) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL4730562 | 0.91 | MAOA (0.67) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL12502050 | 0.91 | MAOA (0.62) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL29778251 | 0.91 | MAOA (0.62) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL989107 | 0.91 | TDP1 (0.71) | TDP1MEN1GAAKMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298022-B1 | NOVEL ANNELATED PHENOXYACETAMIDES | BOEHRINGER INGELHEIM INT (DE) | 2019-06-05 | — | — | EP | disclosed |
| US-10221202-B2 | Annelated phenoxyacetamides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-03-05 | — | — | US | disclosed |
| EP-3298022-A1 | NOVEL ANNELATED PHENOXYACETAMIDES | Boehringer Ingelheim International GmbH (DE) | 2018-03-28 | — | — | EP | disclosed |
| WO-2017028927-A1 | NOVEL ANNELATED PHENOXYACETAMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-02-23 | — | — | WO | disclosed |
| US-20170050992-A1 | NOVEL ANNELATED PHENOXYACETAMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10221202-B2 | Annelated phenoxyacetamides | EP300, NAT1, REN | TDP1 3980/4885MEN1 882/4885GAA 2882/4885 |
| US-20170050992-A1 | NOVEL ANNELATED PHENOXYACETAMIDES | EP300, NAT1, AADAC | TDP1 4037/4885MEN1 1607/4885GAA 2793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.