Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREB1 | P16220 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.55 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18526951 | 0.87 | ABCG2 (0.65) | CREB1L3MBTL1BCHEACHEPPARG | |
| SCHEMBL24514598 | 0.81 | ABCB1 (0.68) | L3MBTL1ACHEABCB1CYP1B1MEN1 | |
| SCHEMBL24514602 | 0.81 | CYP1A1 (0.75) | CREB1BCHEACHEMAPTABCB1 | |
| SCHEMBL16894650 | 0.81 | ABCB1 (0.76) | MAPTABCB1POLHAKR1B1MAOA | |
| SCHEMBL19235588 | 0.81 | ALDH1A1 (0.76) | CREB1PPARGMAPTABCB1POLH | |
| SCHEMBL21206267 | 0.80 | ABCB1 (0.73) | ACHEABCB1CYP1B1MEN1ALDH1A1 | |
| SCHEMBL4649969 | 0.80 | ABCB1 (0.73) | L3MBTL1ACHEABCB1CYP1B1MEN1 | |
| SCHEMBL24514601 | 0.80 | ABCB1 (0.73) | L3MBTL1ACHEABCB1CYP1B1MEN1 | |
| SCHEMBL7156543 | 0.80 | ABCB1 (0.69) | L3MBTL1ACHEABCB1CYP1B1MEN1 | |
| SCHEMBL30376265 | 0.80 | ABCB1 (0.73) | ACHEABCB1CYP1B1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10058582-B2 | Therapeutic molecules and deviates for CRC | ANTARTINA LLC (US) | 2018-08-28 | — | — | US | disclosed |
| EP-3337493-A1 | NEW THERAPEUTIC MOLECULES & DEVIATES FOR CRC | Antartina LLC (US) | 2018-06-27 | — | — | EP | disclosed |
| WO-2017031054-A1 | NEW THERAPEUTIC MOLECULES & DEVIATES FOR CRC | ANTARTINA LLC (US) | 2017-02-23 | — | — | WO | disclosed |
| US-20170049839-A1 | Therapeutic molecules & deviates for CRC | NEOCAGE SL (AD) | 2017-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10058582-B2 | Therapeutic molecules and deviates for CRC | DLD, APC, SEPTIN7 | CREB1 3233/4885L3MBTL1 3546/4885BCHE 3529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.