Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.34 |
| ▸ | CYTH3 | O43739 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | EPN1 | Q9Y6I3 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16561821 | 0.72 | FDPS (0.32) | — | |
| SCHEMBL17933349 | 0.70 | SCN10A (0.39) | APEX1ALDH1A1 | |
| SCHEMBL18534204 | 0.67 | CYTH3 (0.53) | CHRM1PRKAG1PRKAA2PRKAA1PRKAB1 | |
| SCHEMBL5201259 | 0.66 | PDE9A (0.40) | CHRM1PRKAG1PRKAA2PRKAA1PRKAB1 | |
| SCHEMBL3277117 | 0.65 | FDPS (0.47) | CYTH3BTKEPN1 | |
| SCHEMBL23824708 | 0.65 | AOC3 (0.49) | PRKAG1PRKAA2PRKAA1PRKAB1P4HTM | |
| SCHEMBL18534263 | 0.64 | HDAC6 (0.42) | P4HTM | |
| SCHEMBL18534217 | 0.63 | RXRA (0.50) | CHRM1KDM4EP4HTM | |
| SCHEMBL19292204 | 0.62 | TBXAS1 (0.54) | TBXAS1ALDH1A1 | |
| SCHEMBL30620153 | 0.62 | TBXAS1 (0.74) | CHRM1PARP1PARP2PRKAG1PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2976346-B1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | UNIV SHEFFIELD (GB) | 2017-02-22 | — | — | EP | disclosed |