Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 10/20 | 0.50 |
| ▸ | RXRB | P28702 | 10/20 | 0.50 |
| ▸ | RXRG | P48443 | 7/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | C5 | P01031 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4632525 | 0.74 | RXRA (0.54) | RXRARXRBRXRGTSHRNR4A2 | |
| SCHEMBL16561819 | 0.71 | FBP1 (0.34) | — | |
| SCHEMBL3719448 | 0.71 | RXRA (0.51) | RXRARXRBRXRGTSHRNR4A2 | |
| SCHEMBL18169217 | 0.69 | RXRA (0.94) | RXRARXRBRXRGTSHRNR4A2 | |
| SCHEMBL20275214 | 0.68 | RXRA (0.45) | RXRARXRBRXRGTSHRNR4A2 | |
| SCHEMBL6069881 | 0.66 | RXRA (0.76) | RXRARXRBRXRGKDM4ECYP2C19 | |
| SCHEMBL18169172 | 0.66 | RXRA (0.76) | RXRARXRBRXRGTSHRKDM4E | |
| SCHEMBL18169197 | 0.66 | RXRA (0.76) | RXRARXRBRXRGTSHRKDM4E | |
| SCHEMBL18534263 | 0.64 | HDAC6 (0.42) | RXRARXRBRXRGFFAR1P4HTM | |
| SCHEMBL14146507 | 0.64 | RXRA (0.44) | RXRARXRBRXRGTSHRNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2976346-B1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | UNIV SHEFFIELD (GB) | 2017-02-22 | — | — | EP | disclosed |