Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL184556 | 0.95 | KMT2A (0.50) | KMT2AMAPTMEN1TSHRSMN1; SMN2 | |
| SCHEMBL10581958 | 0.90 | KMT2A (0.49) | KMT2AMAPTMEN1TSHRSMN1; SMN2 | |
| Potassium Ion SCHEMBL4430077 | 0.89 | HTT (0.54) | KMT2AMAPTMEN1TSHRSMN1; SMN2 | |
| SCHEMBL8507081 | 0.86 | HTT (0.54) | KMT2AMAPTMEN1TSHRSMN1; SMN2 | |
| SCHEMBL8506452 | 0.86 | HTT (0.54) | KMT2AMAPTMEN1TSHRSMN1; SMN2 | |
| SCHEMBL2230565 | 0.86 | HTT (0.54) | KMT2AMAPTMEN1TSHRSMN1; SMN2 | |
| Potassium Ion SCHEMBL10978421 | 0.81 | L3MBTL1 (0.45) | KMT2AMAPTMEN1TSHRSMN1; SMN2 | |
| SCHEMBL11718322 | 0.80 | KMT2A (0.47) | KMT2AMAPTMEN1TSHRSMN1; SMN2 | |
| SCHEMBL11383001 | 0.79 | L3MBTL1 (0.45) | KMT2AMAPTMEN1TSHRSMN1; SMN2 | |
| Potassium Ion SCHEMBL10978488 | 0.78 | HTT (0.52) | KMT2AMAPTMEN1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2579987-B1 | USE OF THE NATURALLY OCCURRING MAGNETIC COMPONENTS OF ORES | BASF SE (DE) | 2020-03-18 | — | — | EP | disclosed |
| EP-2401084-B1 | CU-MO SEPARATION | BASF SE (DE) | 2019-05-22 | — | — | EP | disclosed |
| EP-2376230-B1 | ENRICHMENT OF VALUABLE ORES FROM MINE WASTE (TAILINGS) | BASF SE (DE) | 2014-07-30 | — | — | EP | disclosed |
| EP-2498913-B1 | METHOD FOR INCREASING EFFICIENCY IN THE ORE SEPARATING PROCESS BY MEANS OF HYDROPHOBIC MAGNETIC PARTICLES BY APPLYING TARGETED MECHANICAL ENERGY | BASF SE (DE) | 2013-11-06 | — | — | EP | disclosed |
| EP-2403648-B1 | MAGNETIC SEPARATION OF NONFERROUS METAL ORES BY MEANS OF MULTI-STAGE CONDITIONING | BASF SE (DE) | 2013-09-04 | — | — | EP | disclosed |
| EP-2403649-B1 | MAGNETIC HYDROPHOBIC AGGLOMERATES | BASF SE (DE) | 2013-08-28 | — | — | EP | disclosed |
| EP-2190584-B1 | PROCESSING RICH ORES USING MAGNETIC PARTICLES | BASF SE (DE) | 2013-06-05 | — | — | EP | disclosed |
| EP-2498913-A1 | METHOD FOR INCREASING EFFICIENCY IN THE ORE SEPARATING PROCESS BY MEANS OF HYDROPHOBIC MAGNETIC PARTICLES BY APPLYING TARGETED MECHANICAL ENERGY | BASF SE (DE) | 2012-09-19 | — | — | EP | disclosed |
| EP-2403649-A1 | MAGNETIC HYDROPHOBIC AGGLOMERATES | BASF SE (DE) | 2012-01-11 | — | — | EP | disclosed |
| EP-2403648-A1 | MAGNETIC SEPARATION OF NONFERROUS METAL ORES BY MEANS OF MULTI-STAGE CONDITIONING | BASF SE (DE) | 2012-01-11 | — | — | EP | disclosed |
| EP-2401084-A1 | CU-MO SEPARATION | BASF SE (DE) | 2012-01-04 | — | — | EP | disclosed |
| EP-2376230-A1 | ENRICHMENT OF VALUABLE ORES FROM MINE WASTE (TAILINGS) | BASF SE (DE) | 2011-10-19 | — | — | EP | disclosed |
| WO-2011058039-A1 | METHOD FOR INCREASING EFFICIENCY IN THE ORE SEPARATING PROCESS BY MEANS OF HYDROPHOBIC MAGNETIC PARTICLES BY APPLYING TARGETED MECHANICAL ENERGY | BASF SE (DE) | 2011-05-19 | — | — | WO | disclosed |
| WO-2010100181-A1 | MAGNETIC SEPARATION OF NONFERROUS METAL ORES BY MEANS OF MULTI-STAGE CONDITIONING | BASF SE (DE) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010100180-A1 | MAGNETIC HYDROPHOBIC AGGLOMERATES | BASF SE (DE) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010097361-A1 | CU-MO SEPARATION | BASF SE (DE) | 2010-09-02 | — | — | WO | disclosed |
| WO-2010066770-A1 | ENRICHMENT OF VALUABLE ORES FROM MINE WASTE (TAILINGS) | BASF SE (DE) | 2010-06-17 | — | — | WO | disclosed |
| EP-2190584-A2 | PROCESSING RICH ORES USING MAGNETIC PARTICLES | BASF SE (DE) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009030669-A2 | PROCESSING RICH ORES USING MAGNETIC PARTICLES | BASF SE (DE) | 2009-03-12 | — | — | WO | disclosed |