Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 6/20 | 0.44 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.43 |
| ▸ | ABAT | P80404 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12441767 | 0.78 | SMN1; SMN2 (0.48) | CA2TAAR1SMN1; SMN2 | |
| SCHEMBL2208306 | 0.76 | TSHR (0.40) | CA1CA2CA12CA4CA6 | |
| SCHEMBL13538144 | 0.76 | CA2 (0.48) | HRH3LOXL2ABATHDAC3HDAC6 | |
| Hydrochloric Acid SCHEMBL22165294 | 0.74 | CA2 (0.46) | HRH3LOXL2ABATHDAC3HDAC6 | |
| SCHEMBL28858779 | 0.74 | PSIP1 (0.42) | HRH3LOXL2PSIP1ABATHDAC3 | |
| SCHEMBL23031966 | 0.73 | ESR1 (0.50) | TAAR1 | |
| SCHEMBL18550519 | 0.73 | LOXL2 (0.47) | LOXL2HDAC6MAPTNOS3NOS1 | |
| SCHEMBL31019757 | 0.73 | LOXL2 (0.39) | HRH3LOXL2PSIP1ABATHDAC3 | |
| SCHEMBL15828 | 0.72 | HRH3 (0.79) | HRH3LOXL2PSIP1ABATCA1 | |
| SCHEMBL1491759 | 0.72 | MEN1 (0.44) | CA1CA2CA12CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226950-A1 | PEPTIDOMIMETIC STAT PROTEIN DEGRADER, COMPOSITION AND USE THEREOF | 杭州和正医药有限公司 | 2023-11-30 | — | — | WO | disclosed |
| CN-117126231-A | Peptoid STAT protein degradation agent, composition and application thereof | 杭州和正医药有限公司 | 2023-11-28 | — | — | CN | disclosed |
| EP-3298022-B1 | NOVEL ANNELATED PHENOXYACETAMIDES | BOEHRINGER INGELHEIM INT (DE) | 2019-06-05 | — | — | EP | disclosed |
| US-10221202-B2 | Annelated phenoxyacetamides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-03-05 | — | — | US | disclosed |
| US-20170313732-A1 | NOVEL ANNELATED PHENOXYACETAMIDES | BOEHRINGER INGELHEIM INT (DE) | 2017-11-02 | — | — | US | disclosed |
| US-20170313732-A1 | NOVEL ANNELATED PHENOXYACETAMIDES | BOEHRINGER INGELHEIM INT (DE) | 2017-11-02 | — | — | US | disclosed |
| WO-2017028927-A1 | NOVEL ANNELATED PHENOXYACETAMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-02-23 | — | — | WO | disclosed |
| US-20170050992-A1 | NOVEL ANNELATED PHENOXYACETAMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-02-23 | — | — | US | disclosed |
| US-20170050992-A1 | NOVEL ANNELATED PHENOXYACETAMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170313732-A1 | NOVEL ANNELATED PHENOXYACETAMIDES | EP300, NAT1, AADAC | HRH3 118/4885LOXL2 3969/4885PSIP1 3689/4885 |
| US-10221202-B2 | Annelated phenoxyacetamides | EP300, NAT1, REN | HRH3 183/4885LOXL2 3510/4885PSIP1 2907/4885 |
| US-20170050992-A1 | NOVEL ANNELATED PHENOXYACETAMIDES | EP300, NAT1, AADAC | HRH3 125/4885LOXL2 3786/4885PSIP1 3419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.