Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 3/20 | 0.33 |
| ▸ | CD14 | P08571 | 3/20 | 0.33 |
| ▸ | LY96 | Q9Y6Y9 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18539819 | 0.86 | — | — | |
| SCHEMBL18539817 | 0.81 | KMT2A (0.34) | LMNAKMT2AMEN1USP2ALOX15 | |
| SCHEMBL15187966 | 0.78 | THRA (0.42) | TLR4CD14LY96POLBLMNA | |
| SCHEMBL12401801 | 0.75 | POLB (0.43) | POLBHTTKDM4EHTR1DRECQL | |
| SCHEMBL15369554 | 0.75 | THRA (0.50) | TLR4CD14LY96KDM4EKMT2A | |
| SCHEMBL15736789 | 0.71 | — | — | |
| SCHEMBL11209960 | 0.71 | NPC1 (0.30) | — | |
| SCHEMBL8201459 | 0.71 | HTR1A (0.43) | TLR4CD14LY96POLBKDM4E | |
| SCHEMBL14594240 | 0.69 | RXRA (0.47) | TLR4CD14LY96LMNAKDM4E | |
| SCHEMBL22634303 | 0.68 | ELOVL1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170051224-A1 | HYDROGENATED POLYMERS WITH A RADIAL STRUCTURE HAVING A CORE BASED ON CALIXARENES AND USE THEREOF IN LUBRICANT COMPOSITIONS | ENI S.P.A. (IT) | 2017-02-23 | — | — | US | disclosed |