Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1857046 | 0.81 | FFAR1 (0.47) | MAOBFFAR1PPARGARMRGPRX4 | |
| SCHEMBL6721633 | 0.80 | MAOB (0.55) | MAOBFFAR1ARMRGPRX4 | |
| SCHEMBL5039923 | 0.80 | ACACB (0.45) | MAOBFFAR1PPARG | |
| SCHEMBL1854031 | 0.79 | BCHE (0.66) | MAOBARPPARA | |
| SCHEMBL5041015 | 0.79 | MAOB (0.50) | MAOBFFAR1ARMRGPRX4 | |
| SCHEMBL255002 | 0.78 | MAOB (0.69) | MAOBARMRGPRX4 | |
| SCHEMBL1850966 | 0.75 | L3MBTL1 (0.62) | MAOBARMRGPRX4 | |
| SCHEMBL2873573 | 0.75 | MAOB (0.69) | MAOBARMRGPRX4 | |
| Ammonia Solution, Strong SCHEMBL6903652 | 0.73 | MAOB (0.67) | MAOBARMRGPRX4 | |
| SCHEMBL14786201 | 0.73 | MAOB (0.71) | MAOBFFAR1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470102-B1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | MERCK SERONO SA (CH) | 2011-05-25 | — | — | EP | disclosed |