Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPRB | P23467 | 1/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1854031 | 0.85 | BCHE (0.66) | MAOBAR | |
| SCHEMBL255002 | 0.84 | MAOB (0.69) | MAOBARMRGPRX4MAOAPTPN1 | |
| SCHEMBL5041015 | 0.82 | MAOB (0.50) | MAOBARMRGPRX4PTPN1PTPN6 | |
| SCHEMBL1850966 | 0.81 | L3MBTL1 (0.62) | MAOBARMRGPRX4HRH3 | |
| SCHEMBL2873573 | 0.81 | MAOB (0.69) | MAOBARMRGPRX4PTPN1PTPN6 | |
| SCHEMBL1854030 | 0.80 | MAOB (0.50) | MAOBARMRGPRX4FFAR1 | |
| Ammonia Solution, Strong SCHEMBL6903652 | 0.79 | MAOB (0.67) | MAOBARMRGPRX4MAOAPTPN1 | |
| SCHEMBL14786201 | 0.79 | MAOB (0.71) | MAOBMAOAPTPN1PTPN6PTPN11 | |
| SCHEMBL6717178 | 0.78 | RAB9A (0.67) | MAOBARMRGPRX4 | |
| SCHEMBL1854045 | 0.78 | MAOB (0.50) | MAOBARMRGPRX4PTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470102-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | Applied Research Systems ARS Holding N.V. (AN) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064376-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-08-07 | — | — | WO | disclosed |