Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPRB | P23467 | 1/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8676362 | 0.83 | LMNA (0.56) | MAOBFFAR1 | |
| SCHEMBL6721633 | 0.82 | MAOB (0.55) | MAOBARPTPN1MRGPRX4PTPN6 | |
| SCHEMBL1854031 | 0.81 | BCHE (0.66) | MAOBAR | |
| SCHEMBL255002 | 0.80 | MAOB (0.69) | MAOBARPTPN1MRGPRX4PTPN6 | |
| SCHEMBL4811925 | 0.80 | ALDH1A1 (0.48) | MAOB | |
| SCHEMBL1854030 | 0.79 | MAOB (0.50) | MAOBARMRGPRX4FFAR1 | |
| SCHEMBL1850966 | 0.77 | L3MBTL1 (0.62) | MAOBARMRGPRX4 | |
| SCHEMBL2873573 | 0.77 | MAOB (0.69) | MAOBARPTPN1MRGPRX4PTPN6 | |
| SCHEMBL28757558 | 0.77 | ALDH1A1 (0.48) | MAOB | |
| SCHEMBL27696302 | 0.76 | F2 (0.54) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |