SCHEMBL18540403

SCHEMBL18540403

C[SiH](C)c1ccc(-c2cccc(N(c3ccccc3)c3cccc(-c4ccc([Si](C)(C)c5ccccc5)cn4)c3)c2)nc1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.31
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18540410 0.83 CYP11B1 (0.40) CYP11B1ESR1ESR2
SCHEMBL18540375 0.80 CYP11B1 (0.36) CYP11B1
SCHEMBL18540383 0.76 HSD17B1 (0.39) CYP11B1
SCHEMBL24203501 0.73 ESR1 (0.42) ESR1ESR2
SCHEMBL24203504 0.73 ESR1 (0.42) ESR1ESR2
SCHEMBL24203502 0.73 ESR1 (0.42) ESR1ESR2
SCHEMBL17952949 0.73 HSD17B1 (0.53) CYP11B1
SCHEMBL18540405 0.72 GABRG2 (0.43) ESR1ESR2
SCHEMBL18540391 0.72 CYP11B1 (0.30) CYP11B1
SCHEMBL18540401 0.71 KDM1A (0.36) CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220093880-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO LTD (KR) 2022-03-24 US disclosed
US-11211571-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-12-28 US disclosed
US-20170054095-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD., (KR) 2017-02-23 US disclosed
US-20170054095-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD., (KR) 2017-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220093880-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, LEF1, POU2F1 CYP11B1 766/4885ESR1 265/4885ESR2 775/4885
US-11211571-B2 Organometallic compound and organic light-emitting device including the same CRY1, LEF1, POU2F1 CYP11B1 766/4885ESR1 265/4885ESR2 775/4885
US-20170054095-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, LEF1, POU2F1 CYP11B1 766/4885ESR1 265/4885ESR2 775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.