SCHEMBL18546641

SCHEMBL18546641

c1nc(CC2CO2)cn1CC1CO1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.35
HBB P68871 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
KDM4C Q9H3R0 1/20 0.33
JAK2 O60674 1/20 0.32
JAK1 P23458 1/20 0.32
TYK2 P29597 1/20 0.32
JAK3 P52333 1/20 0.32
CPB2 Q96IY4 1/20 0.30
MAPT P10636 1/20 0.30
DHFR P00374 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4856764 0.58
SCHEMBL10641635 0.57
SCHEMBL623468 0.57
SCHEMBL6531073 0.56 CYP1A2 (0.38) TP53SMN1; SMN2
SCHEMBL132428 0.55 ALDH1A1 (0.37) TP53HBBSMN1; SMN2MAPT
SCHEMBL2014742 0.55 ALDH1A1 (0.36) TP53HBBSMN1; SMN2
Teroxirone SCHEMBL2097151 0.54 TP53 (1.00) TP53HBBSMN1; SMN2MAPTDHFR
Teroxirone SCHEMBL4470513 0.54 TP53 (1.00) TP53HBBSMN1; SMN2MAPTDHFR
SCHEMBL21119006 0.54 TP53 (0.64) TP53HBBSMN1; SMN2MAPTDHFR
SCHEMBL21119007 0.54 TP53 (0.64) TP53HBBSMN1; SMN2MAPTDHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10197930-B2 Electrophotographic member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2019-02-05 US disclosed
US-10197930-B2 Electrophotographic member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2019-02-05 US disclosed
US-20170060007-A1 ELECTROPHOTOGRAPHIC MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2017-03-02 US disclosed
US-20170060007-A1 ELECTROPHOTOGRAPHIC MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2017-03-02 US disclosed
US-20170060007-A1 ELECTROPHOTOGRAPHIC MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2017-03-02 US disclosed