SCHEMBL132428

SCHEMBL132428

c1c(CC2CO2)cc(CC2CO2)cc1CC1CO1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
TP53 P04637 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
CYP3A4 P08684 2/20 0.37
TSHR P16473 1/20 0.37
HIF1A Q16665 1/20 0.37
TDP1 Q9NUW8 2/20 0.36
HBB P68871 1/20 0.35
MAPT P10636 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7142635 0.85 ALDH1A1 (0.45) ALDH1A1TP53SMN1; SMN2CYP3A4TSHR
SCHEMBL131333 0.82 TDP1 (0.38) ALDH1A1TP53SMN1; SMN2CYP3A4TSHR
SCHEMBL11854549 0.79 MAOA (0.45) ALDH1A1CYP3A4GLA
SCHEMBL5377497 0.78
SCHEMBL15537329 0.78 GABRA1 (0.37) ALDH1A1TP53TSHRHIF1AMAPT
SCHEMBL2754953 0.78 ALDH1A1 (0.39) ALDH1A1TP53SMN1; SMN2CYP3A4TSHR
SCHEMBL873444 0.76 SLC6A2 (0.50) TSHRTDP1MEN1KMT2A
SCHEMBL13990310 0.76 MGLL (0.42) ALDH1A1TP53SMN1; SMN2CYP3A4TSHR
SCHEMBL14063010 0.76 MGLL (0.38)
SCHEMBL1673434 0.76 CYP1A2 (0.34) ALDH1A1TP53SMN1; SMN2CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 440 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12617238-B2 Pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-05-05 US disclosed
EP-4722000-A1 TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-04-08 EP disclosed
US-12589615-B2 Pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-03-31 US disclosed
EP-4706987-A1 TIRE Sumitomo Rubber Industries, Ltd. (JP) 2026-03-11 EP disclosed
EP-4706982-A1 TIRE Sumitomo Rubber Industries, Ltd. (JP) 2026-03-11 EP disclosed
EP-4706979-A1 TIRE Sumitomo Rubber Industries, Ltd. (JP) 2026-03-11 EP disclosed
EP-4706984-A1 TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-03-11 EP disclosed
EP-4706983-A1 TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-03-11 EP disclosed
EP-4703147-A1 TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-03-04 EP disclosed
EP-4703152-A1 TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-03-04 EP disclosed
US-20090124730-A1 Modified polymer and composition containing the same ASAHI KASEI CHEMICALS CORPORATION 2009-05-14 US disclosed
EP-2045272-A1 MODIFIED CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING THE SAME Asahi Kasei Chemicals Corporation (JP) 2009-04-08 EP disclosed
US-7498387-B2 Modified polymers and compositions containing the same ASAHI KASEI CHEMICALS CORPORATION (JP) 2009-03-03 US disclosed
EP-1942120-A1 CONJUGATED DIENE POLYMER AND PROCESS FOR PRODUCTION THEREOF Asahi Kasei Chemicals Corporation (JP) 2008-07-09 EP disclosed
EP-1153972-B1 RUBBER COMPOSITION ASAHI CHEMICAL IND (JP) 2006-05-03 EP disclosed
US-6969739-B1 Rubber composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2005-11-29 US disclosed
US-20050171276-A1 Modified polymers and compositions containing the same ASAHI KASEI CHEMICALS CORPORATION (JP) 2005-08-04 US disclosed
US-6906152-B2 Rubber compositions ASAHI KASEI KABUSHIKI KAISHA (JP) 2005-06-14 US disclosed
US-20030199669-A1 Synthetic or natural rubbers comprising conjugated homo/co-and/or terpolymers having improved balance between low rolling resistance and wet skid resistance, for use as automobile tires ASAHI KASEI KABUSHIKI KAISHA 2003-10-23 US disclosed
EP-1153972-A1 RUBBER COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2001-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12589615-B2 Pneumatic tire LBR, TERF2, TLN1 ALDH1A1 3840/4885TP53 3048/4885SMN1; SMN2 1789/4885
US-12617238-B2 Pneumatic tire CCT4, CCT7, CCNE2 ALDH1A1 4505/4885TP53 2187/4885SMN1; SMN2 1412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.