Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 4/20 | 0.48 |
| ▸ | BRS3 | P32247 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | TEAD1 | P28347 | 3/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29644344 | 0.82 | ACACB (0.59) | ACACBCARM1PRMT6PRMT1 | |
| SCHEMBL28739031 | 0.82 | ACACB (0.59) | ACACBCARM1PRMT6PRMT1 | |
| Bromide SCHEMBL7984185 | 0.80 | ALDH1A1 (0.51) | KDM4EALDH1A1GAALMNADRD2 | |
| SCHEMBL7987036 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1GAALMNADRD2 | |
| SCHEMBL1854687 | 0.78 | KDM4E (0.54) | KDM4EALDH1A1GAALMNADRD2 | |
| SCHEMBL697853 | 0.77 | KDM4E (0.53) | KDM4EALDH1A1GAALMNADRD2 | |
| SCHEMBL2439744 | 0.77 | KDM4E (0.62) | KDM4EALDH1A1GAALMNADRD2 | |
| SCHEMBL1853855 | 0.76 | FFAR1 (0.51) | KDM4EALDH1A1GAALMNADRD2 | |
| SCHEMBL6974043 | 0.76 | KDM4E (0.54) | KDM4EALDH1A1GAALMNADRD2 | |
| SCHEMBL16593829 | 0.75 | PTGER4 (0.58) | KDM4EALDH1A1GAALMNADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |
| US-20100041891-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041891-A1 | AMIDE COMPOUND | GPR52, GPR132, NR5A2 | KDM4E 3467/4885ALDH1A1 2005/4885GAA 4210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.