Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
| ▸ | GABRE | P78334 | 2/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.33 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 8/20 | 0.32 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2223205 | 0.95 | GABRP (0.37) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL261164 | 0.84 | LMNA (0.37) | ALDH1A1 | |
| SCHEMBL2637205 | 0.84 | LMNA (0.37) | ALDH1A1 | |
| SCHEMBL261165 | 0.84 | LMNA (0.37) | ALDH1A1 | |
| SCHEMBL262272 | 0.80 | HTT (0.35) | ALDH1A1 | |
| SCHEMBL3467830 | 0.80 | HTT (0.35) | ALDH1A1 | |
| SCHEMBL263453 | 0.80 | HTT (0.35) | ALDH1A1 | |
| SCHEMBL261441 | 0.80 | HTT (0.35) | ALDH1A1 | |
| SCHEMBL260952 | 0.80 | HTT (0.35) | ALDH1A1 | |
| SCHEMBL2920755 | 0.79 | HTT (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10260059-B2 | Nitrilase from arabis alpina, its encoding gene, vector, recombinant bacterial strain and uses thereof | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2019-04-16 | — | — | US | disclosed |
| US-10100297-B2 | Nitrilase from arabis alpina, its encoding gene, vector, recombinant bacterial strain and uses thereof | Zhejiang Chiral Medicine Chemicals Co. Ltd. (CN) | 2018-10-16 | — | — | US | disclosed |
| US-20170355975-A1 | NITRILASE FROM ARABIS ALPINA, ITS ENCODING GENE, VECTOR, RECOMBINANT BACTERIAL STRAIN AND USES THEREOF | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2017-12-14 | — | — | US | disclosed |
| US-20170355976-A1 | NITRILASE FROM ARABIS ALPINA, ITS ENCODING GENE, VECTOR, RECOMBINANT BACTERIAL STRAIN AND USES THEREOF | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2017-12-14 | — | — | US | disclosed |
| US-20170058274-A1 | NITRILASE FROM ARABIS ALPINA, ITS ENCODING GENE, VECTOR, RECOMBINANT BACTERIAL STRAIN AND USES THEREOF | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2017-03-02 | — | — | US | disclosed |