Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.37 |
| ▸ | GABRD | O14764 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.37 |
| ▸ | GABRE | P78334 | 2/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 9/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18548797 | 0.95 | GABRP (0.33) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7343378 | 0.83 | FOLH1 (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28304232 | 0.83 | FOLH1 (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL268072 | 0.83 | MEN1 (0.37) | ALDH1A1MEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL268058 | 0.83 | MEN1 (0.37) | ALDH1A1MEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL268067 | 0.83 | MEN1 (0.37) | ALDH1A1MEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL31164267 | 0.83 | MEN1 (0.37) | ALDH1A1MEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL28949225 | 0.78 | FOLH1 (0.35) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL261164 | 0.76 | LMNA (0.37) | ALDH1A1MEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL2637205 | 0.76 | LMNA (0.37) | ALDH1A1MEN1GAAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117802069-B | Du Bangshi thermomyces lipase mutant, coding gene, engineering bacterium and application thereof | 新余学院 | 2025-01-28 | — | — | CN | claimed |
| CN-117802069-A | Du Bangshi thermomyces lipase mutant, coding gene, engineering bacterium and application thereof | 新余学院 | 2024-04-02 | — | — | CN | claimed |
| CN-106676084-B | A kind of lipase mutant, encoding gene and its application from thermophilic ankle section bacterium | 浙江工业大学 | 2019-11-29 | — | — | CN | claimed |
| CN-106591258-B | A kind of lipase gene, carrier, engineering bacteria and its application | 新余学院 | 2019-06-04 | — | — | CN | claimed |
| CN-121874156-A | Lipase mutant and application thereof | 青岛蔚蓝生物集团有限公司 | 2026-04-17 | — | — | CN | disclosed |
| CN-121874157-A | Lipase mutant | 青岛蔚蓝生物集团有限公司 | 2026-04-17 | — | — | CN | disclosed |
| CN-120082537-B | Lipase mutant | 青岛蔚蓝生物集团有限公司 | 2026-03-17 | — | — | CN | disclosed |
| CN-120082537-A | Lipase mutant | 青岛蔚蓝生物集团有限公司 | 2025-06-03 | — | — | CN | disclosed |
| US-20250084395-A1 | ENGINEERED NITRILASES FOR BIOCATALYSIS | KCAT ENZYMATIC PRIVATE LIMITED (IN) | 2025-03-13 | — | — | US | disclosed |
| CN-117802069-B | Du Bangshi thermomyces lipase mutant, coding gene, engineering bacterium and application thereof | 新余学院 | 2025-01-28 | — | — | CN | disclosed |
| CN-117802069-B | Du Bangshi thermomyces lipase mutant, coding gene, engineering bacterium and application thereof | 新余学院 | 2025-01-28 | — | — | CN | disclosed |
| CN-117802069-A | Du Bangshi thermomyces lipase mutant, coding gene, engineering bacterium and application thereof | 新余学院 | 2024-04-02 | — | — | CN | disclosed |
| WO-2009044409-A2 | NOVEL RESOLUTION PROCESS FOR PREGABALIN | NATCO PHARMA LIMITED (IN) | 2009-04-09 | — | — | WO | disclosed |
| EP-1912931-A2 | PREPARATION OF (S)-PREGABALIN-NITRILE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2008-04-23 | — | — | EP | disclosed |
| EP-1913147-A2 | THE USE OF ENZYMATIC RESOLUTION FOR THE PREPARATION OF INTERMEDIATES OF PREGABALIN | Teva Pharmaceutical Industries Ltd (IL) | 2008-04-23 | — | — | EP | disclosed |
| US-20080026433-A1 | Use of enzymatic resolution for the preparation of intermediates of pregabalin | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2008-01-31 | — | — | US | disclosed |
| US-20080015385-A1 | Preparation of (S)-pregabalin-nitrile | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2008-01-17 | — | — | US | disclosed |
| WO-2007143152-A2 | PREPARATION OF (S)-PREGABALIN-NITRILE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2007-12-13 | — | — | WO | disclosed |
| WO-2007143113-A2 | THE USE OF ENZYMATIC RESOLUTION FOR THE PREPARATION OF INTERMEDIATES OF PREGABALIN | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2007-12-13 | — | — | WO | disclosed |
| US-20060270871-A1 | POLYMORPHIC FORM I OF PREGABALIN AND PROCESSES FOR ITS PREPARATION | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015385-A1 | Preparation of (S)-pregabalin-nitrile | GABRE, GAP43, RIMKLA | GABRP 11/4885GABRD 9/4885GABRA1 21/4885 |
| US-20060270871-A1 | POLYMORPHIC FORM I OF PREGABALIN AND PROCESSES FOR ITS PREPARATION | GABRP, GABRB1, GABRB2 | GABRP 1/4885GABRD 14/4885GABRA1 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.