Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 10/20 | 0.41 |
| ▸ | ACE | P12821 | 7/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.37 |
| ▸ | PSAT1 | Q9Y617 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16932216 | 0.82 | MME (0.46) | MMEACEACE2CPA1ALDH1A1 | |
| SCHEMBL16932215 | 0.82 | MME (0.46) | MMEACEACE2CPA1ALDH1A1 | |
| Hydroxyamine SCHEMBL30526974 | 0.80 | MME (0.44) | MMEACEACE2CPA1ALDH1A1 | |
| SCHEMBL15085660 | 0.77 | ALDH1A1 (0.49) | MMEACEACE2CPA1ALDH1A1 | |
| SCHEMBL6792263 | 0.77 | MTNR1A (0.38) | ALDH1A1FFAR1 | |
| SCHEMBL6792267 | 0.77 | MTNR1A (0.38) | ALDH1A1FFAR1 | |
| SCHEMBL4064873 | 0.73 | ALPI (0.43) | ALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL18344466 | 0.73 | ALPI (0.43) | ALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL5066181 | 0.73 | ALPI (0.43) | ALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL18576716 | 0.72 | CTSS (0.54) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017033128-A1 | BIPHENYL-SUBSTITUED 4-AMINO-BUTYRIC ACID DERIVATIVES AND THEIR USE IN THE SYNTHESIS OF NEP INHIBITORS | NOVARTIS AG (CH) | 2017-03-02 | — | — | WO | disclosed |