SCHEMBL18565481

SCHEMBL18565481

Cn1c2cccc(-c3ccc4c(c3)C3(c5ccccc5-c5ccccc53)c3ccccc3-4)c2c2c3ccccc3c3ccccc3c21

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 1/20 0.35
FTO Q9C0B1 1/20 0.35
RET P07949 1/20 0.33
IDO1 P14902 2/20 0.33
HSP90AA1 P07900 1/20 0.33
PDK2 Q15119 6/20 0.32
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
PKM P14618 1/20 0.30
MAPK1 P28482 1/20 0.30
RAB9A P51151 1/20 0.30
MDM2 Q00987 1/20 0.30
MCL1 Q07820 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18565480 0.93 ALKBH5 (0.33) ALKBH5FTORETIDO1HSP90AA1
SCHEMBL18565475 0.89 ALKBH5 (0.35) ALKBH5FTORETIDO1HSP90AA1
SCHEMBL18565469 0.85 PDK2 (0.33) PDK2
SCHEMBL18565370 0.85 ALKBH5 (0.45) ALKBH5FTORETIDO1HSP90AA1
SCHEMBL18565378 0.85 GPR3 (0.40) RETPDK2MAPTKDM4EALDH1A1
SCHEMBL18587883 0.84 ALKBH5 (0.41) ALKBH5FTORETIDO1HSP90AA1
SCHEMBL18565465 0.84 MAOB (0.37) ALKBH5FTORETIDO1HSP90AA1
SCHEMBL18565477 0.84 PDK2 (0.33) ALKBH5FTORETIDO1HSP90AA1
SCHEMBL18565451 0.82 FLT3 (0.33) PDK2MAPTKDM4EPKMMAPK1
SCHEMBL18588040 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-05-14 US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device EED, BMI1, CD99 ALKBH5 265/4885FTO 202/4885RET 1581/4885
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE EED, BMI1, CD99 ALKBH5 265/4885FTO 202/4885RET 1581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.