SCHEMBL18565451

SCHEMBL18565451

Cn1c2cccc(-c3ccc4c(c3)C3(c5ccccc5-c5ccccc53)c3ccccc3-4)c2c2c3ccccc3ccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
MAPK1 P28482 1/20 0.33
PTGES O14684 1/20 0.32
GPR3 P46089 1/20 0.32
PDK2 Q15119 3/20 0.32
HTT P42858 1/20 0.32
TERT O14746 1/20 0.32
NTSR1 P30989 2/20 0.31
GAA P10253 1/20 0.31
PKM P14618 1/20 0.31
CASP1 P29466 1/20 0.31
GALK1 P51570 1/20 0.31
BLM P54132 1/20 0.31
CASP7 P55210 1/20 0.31
HSD17B10 Q99714 1/20 0.31
SAE1 Q9UBE0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18565448 0.94 PTGES (0.32) FLT3MAPTKMT2AKDM4EMEN1
SCHEMBL18565446 0.89 MAPT (0.35) FLT3MAPTKMT2AKDM4EMEN1
SCHEMBL18565435 0.87 KDM4E (0.32) FLT3MAPTKMT2AKDM4EMEN1
SCHEMBL18565444 0.87 NQO2 (0.33) MAPTKMT2AKDM4EMEN1MAPK1
SCHEMBL18565378 0.86 GPR3 (0.40) MAPTKMT2AKDM4EMEN1GPR3
SCHEMBL18565442 0.86 RXRA (0.34) FLT3MAPTKMT2AKDM4EMEN1
SCHEMBL18565418 0.84 LMNA (0.34) MAPTKMT2AKDM4EMEN1PDK2
SCHEMBL18588316 0.82 RXRA (0.30)
SCHEMBL18565379 0.82 GPR3 (0.36) MAPTKMT2AKDM4EMEN1GPR3
SCHEMBL18565481 0.82 ALKBH5 (0.35) MAPTKDM4EMAPK1PDK2PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-05-14 US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device EED, BMI1, CD99 FLT3 2660/4885MAPT 1057/4885KMT2A 461/4885
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE EED, BMI1, CD99 FLT3 2660/4885MAPT 1057/4885KMT2A 461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.