Sugi Predict

Sugi Predict / Compounds / SCHEMBL18565378

SCHEMBL18565378

SCHEMBL18565378

Cn1c2ccccc2c2c(-c3ccc4c(c3)C3(c5ccccc5-c5ccccc53)c3ccccc3-4)cccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GPR3 P46089 1/20 0.40
▸ MAPT P10636 3/20 0.38
▸ HTT P42858 2/20 0.38
▸ NQO2 P16083 1/20 0.36
▸ HSD17B10 Q99714 2/20 0.35
▸ KDM4E B2RXH2 2/20 0.35
▸ PDK2 Q15119 6/20 0.35
▸ GABRP O00591 1/20 0.34
▸ GABRD O14764 1/20 0.34
▸ GABRA1 P14867 1/20 0.34
▸ GABRB1 P18505 1/20 0.34
▸ GABRG2 P18507 1/20 0.34
▸ GABRB3 P28472 1/20 0.34
▸ GABRA5 P31644 1/20 0.34
▸ GABRA3 P34903 1/20 0.34
▸ GABRA2 P47869 1/20 0.34
▸ GABRB2 P47870 1/20 0.34
▸ GABRA4 P48169 1/20 0.34
▸ GABRE P78334 1/20 0.34
▸ GABRA6 Q16445 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18565379 0.92 GPR3 (0.36) GPR3MAPTHTTNQO2HSD17B10
SCHEMBL18565376 0.88 GPR3 (0.39) GPR3MAPTHTTNQO2HSD17B10
SCHEMBL18565418 0.87 LMNA (0.34) MAPTKDM4EPDK2MEN1ALDH1A1
SCHEMBL18565451 0.86 FLT3 (0.33) GPR3MAPTHTTHSD17B10KDM4E
SCHEMBL18565481 0.85 ALKBH5 (0.35) MAPTHSD17B10KDM4EPDK2RET
SCHEMBL18565370 0.84 ALKBH5 (0.45) GPR3MAPTHTTHSD17B10KDM4E
SCHEMBL18565368 0.83 RXRA (0.48) GPR3MAPTHTTHSD17B10KDM4E
SCHEMBL13433119 0.83 GPR3 (0.46) GPR3MAPTHTTHSD17B10KDM4E
SCHEMBL17125533 0.83 GPR3 (0.46) GPR3MAPTHTTHSD17B10KDM4E
SCHEMBL18588308 0.83 GPR3 (0.47) GPR3MAPTHTTNQO2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-05-14 — — US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 — — US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device EED, BMI1, CD99 GPR3 3915/4885MAPT 1057/4885HTT 1552/4885
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE EED, BMI1, CD99 GPR3 3915/4885MAPT 1057/4885HTT 1552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.